Synthesis of chalcones derivatives and their biological activities: a review
NAA Elkanzi, H Hrichi, RA Alolayan, W Derafa… - ACS …, 2022 - ACS Publications
Chalcone derivatives are considered valuable species because they possess a
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …
[HTML][HTML] Bis-chalcones: A review of synthetic methodologies and anti-inflammatory effects
Chalcones are bioactive molecules of natural and synthetic sources, whose
physicochemical properties, reactivity, and biological activities are well-known among the …
physicochemical properties, reactivity, and biological activities are well-known among the …
Synthesis and biological activities of novel chalcone derivatives containing pyrazole oxime ethers
D Hu, N Zhang, Q Zhou, Y Zhou, C Gong, Y Zhang… - Fitoterapia, 2023 - Elsevier
A series of novel chalcone derivatives containing pyrazole oxime ethers were designed and
synthesized. The structures of all the target compounds were determined by NMR and …
synthesized. The structures of all the target compounds were determined by NMR and …
Non-small cell lung cancer sensitisation to platinum chemotherapy via new thiazole-triazole hybrids acting as dual T-type CCB/MMP-9 inhibitors
Cisplatin remains the unchallenged standard therapy for NSCLC. However, it is not
completely curative due to drug resistance and oxidative stress-induced toxicity. Drug …
completely curative due to drug resistance and oxidative stress-induced toxicity. Drug …
Synthesis and In vitro evaluation of bichalcones as novel anti-toxoplasma agents
F Mazzone, MKT Klischan, J Greb, SHJ Smits… - Frontiers in …, 2024 - frontiersin.org
Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii, an apicomplexan
parasite that infects approximately a third of the world's human population. This disease can …
parasite that infects approximately a third of the world's human population. This disease can …
[HTML][HTML] Design, synthesis and biological activity of novel chalcone derivatives containing indole
D Hu, N Zhang, Y Zhang, C Yuan, C Gong… - Arabian Journal of …, 2023 - Elsevier
In this study, 24 chalcone derivatives containing indole were designed and synthesized.
Some of the target compounds exhibited significant antiviral and antibacterial effects. The …
Some of the target compounds exhibited significant antiviral and antibacterial effects. The …
Photoinduced, Metal-Free Hydroacylation of Aromatic Alkynes for Synthesis of α,β-Unsaturated Ketones via C(sp3)–H Functionalization
Despite the notable advancements made over the past decade in achieving carbon–carbon
bonds by transition-metal-catalyzed cross-coupling processes, metal-free cross-coupling …
bonds by transition-metal-catalyzed cross-coupling processes, metal-free cross-coupling …
Synthesis of some chalcones derivatives series and their antituberculosis activity
Chalcone is an important biosynthetic precursor, due to the diverse pharmacological
activities. The aim of this current study was to synthesize 14 new chalcone derivatives …
activities. The aim of this current study was to synthesize 14 new chalcone derivatives …
Versatile carrier-free binary nanodrug based on metformin/epigallocatechin gallate nanoparticles: exploring its properties and potential in cancer treatment
H Zou, EK Bian, J He, W Wu, C Deng - Biomaterials Science, 2025 - pubs.rsc.org
Epigallocatechin gallate (EGCG), an important active component extracted from green tea,
has attracted much attention due to its multiple biological activities such as antioxidant …
has attracted much attention due to its multiple biological activities such as antioxidant …
Probing the Fascinating Role of Eu-AgNPs in the Synthesis of Bioactive Substituted Chalcones as a Green Matrix and Study of Their Biological Potential
P Singh, P Yadav, S Bala, J Kaur - Journal of Organometallic Chemistry, 2025 - Elsevier
The demand of environment benign and biologically active nanomaterials has spurred the
development of green synthesis methodologies. The aim of present study was to develop a …
development of green synthesis methodologies. The aim of present study was to develop a …