Influence of inoculum type and cultivation conditions on natamycin production by Streptomyces natalensis

HA El‐Enshasy, MA Farid… - Journal of Basic …, 2000 - Wiley Online Library
This study demonstrates the effect of cultivation conditions on the production of natamycin.
Of these conditions, the effect of oxygen limitation and type of inoculum were extensively …

Improved Erythromycin Production in a Genetically Engineered Industrial Strain of Saccharopolyspora erythraea

W Minas, P Brünker, PT Kallio… - Biotechnology …, 1998 - Wiley Online Library
An industrial erythromycin production strain of Saccharopolyspora erythraea spp. was used
to demonstrate that careful genetic engineering can significantly improve productivity. The …

Process development and metabolic engineering for the overproduction of natural and unnatural polyketides

R McDaniel, P Licari, C Khosla - Metabolic Engineering, 2001 - Springer
Polyketide natural products are a rich source of bioactive substances that have found
considerable use in human health and agriculture. Their complex structures require that they …

Environmental factors drive microbial succession and huangjiu flavor formation during raw wheat qu fermentation

S Liu, Y Zhou, Z Zhou, Z Zhou, X Han, Y Xu, J Mao - Food Bioscience, 2023 - Elsevier
As the core raw material of huangjiu (Chinese rice wine) production and brewing, changes
of physichemical factors during the fermentation process significantly affect the succession …

Kinetics of cell growth and cyclosporin A production by Tolypocladium inflatum when scaling up from shake flask to bioreactor

H El Enshasy, YA Fattah, A Atta, M Anwar… - … of microbiology and …, 2008 - koreascience.kr
The kinetics of cell growth and Cyclosporin A (Cyc A) production by Tolypocladium inflatum
were studied in shake flasks and bioreactors under controlled and uncontrolled pH …

Improved production of erythromycin by Saccharopolyspora erythraea by various plant oils

J Hamedi, F Malekzadeh, V Niknam - Biotechnology letters, 2002 - Springer
Various plant oils (50 gl− 1) increased the production of erythromycin by Saccharopolyspora
erythraea. Maximum titer of erythromycin in media containing black cherry kernel, walnut …

Studies on the interaction of fermentation and microfiltration operations: Erythromycin recovery from Saccharopolyspora erythraea fermentation broths

JL Davies, F Baganz, AP Ison… - Biotechnology and …, 2000 - Wiley Online Library
Abstract Changes in fermentation media not only affect the performance of the fermentation
itself (with regard to the kinetics of biomass and product formation and the yields obtained) …

[HTML][HTML] Determination of erythromycins in fermentation broth using liquid phase extraction with back extraction combined with high performance liquid …

F Kamarei, H Attar, S Nikjah, M Goodarzi - Arabian Journal of Chemistry, 2014 - Elsevier
Liquid phase extraction with back extraction (LPE-BE) combined with high performance
liquid chromatography-diode array detection (HPLC-DAD) was applied for the extraction …

After a decade of progress, an expanded role for metabolic engineering

G Stephanopoulos, RT Gill - Metabolic engineering, 2001 - Springer
Over the past decade, metabolic engineering has emerged as an active and distinct
discipline characterized by its over-arching emphasis on integration. In practice, metabolic …

Turbulent breakage of filamentous bacteria in mechanically agitated batch culture

SM Heydarian, AP Ison, MD Lilly… - Chemical engineering …, 2000 - Elsevier
Turbulent breakage of the S. erythraea filamentous actinomycete has been studied using a 7
L laboratory scale and a 450 l pilot scale mechanically stirred fermenter. A model of hyphal …