The ability of the brain to store and process information relies on changing the strength of
connections between neurons. Synaptic facilitation is a form of short-term plasticity that …

▪ Abstract Synaptic transmission is a dynamic process. Postsynaptic responses wax and
wane as presynaptic activity evolves. This prominent characteristic of chemical synaptic …

Chemical synapses are not static. Postsynaptic potentials (PSPs) wax and wane, depending
on the recent history of presynaptic activity. At some synapses PSPs grow during repetitive …

Voltage-gated calcium (Ca 2+) channels initiate release of neurotransmitters at synapses,
and regulation of presynaptic Ca 2+ channels has a powerful influence on synaptic strength …

Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …

Short-term facilitation is a widely observed form of synaptic enhancement that is not well
understood. Although presynaptic calcium has long been implicated in this process, its role …

Skeletal Muscle: Form and Function, Second Edition, provides readers with a detailed
understanding of the different facets of muscle physiology. Meticulously researched and …

A number of calcium buffers were examined for their ability to reduce evoked transmitter
release when injected into the presynaptic terminal of the squid giant synapse. Injection of …

Activation of presynaptic receptors for a variety of neurotransmitters and neuromodulators
inhibits transmitter release at many synapses. Such presynaptic inhibition might serve as a …

Synapses show widely varying degrees of short-term facilitation and depression. Several
mechanisms have been proposed to underlie short-term plasticity, but the contributions of …