[HTML][HTML] Mechanical regulation of bone regeneration during distraction osteogenesis

R Fu, Y Feng, Y Liu, H Yang - Medicine in novel technology and devices, 2021 - Elsevier
Distraction osteogenesis (DO) is a mechanobiological process of regenerating bone tissue
by tension stress. DO is used clinically to lengthen bones or to treat critical size bone …

Preclinical testing of drug delivery systems to bone

M Van Griensven - Advanced drug delivery reviews, 2015 - Elsevier
Bone defects do not heal in 5–10% of the fractures. In order to enhance bone regeneration,
drug delivery systems are needed. They comprise a scaffold with or without inducing factors …

[HTML][HTML] The investigation of bone fracture healing under intramembranous and endochondral ossification

S Ghimire, S Miramini, G Edwards, R Rotne, J Xu… - Bone reports, 2021 - Elsevier
After trauma, fractured bone starts healing directly through bone union or indirectly through
callus formation process. Intramembranous and endochondral ossification are two …

Bringing computational models of bone regeneration to the clinic

A Carlier, L Geris, J Lammens… - … : Systems Biology and …, 2015 - Wiley Online Library
Although the field of bone regeneration has experienced great advancements in the last
decades, integrating all the relevant, patient‐specific information into a personalized …

Enhancing the efficiency of distraction osteogenesis through rate-varying distraction: A computational study

R Fu, Y Feng, D Bertrand, T Du, Y Liu… - International journal of …, 2021 - mdpi.com
Distraction osteogenesis (DO) is a mechanobiological process of producing new bone and
overlying soft tissues through the gradual and controlled distraction of surgically separated …

Improved weight bearing during gait at 6 weeks post-surgery with an angle stable locking system after distal tibial fracture

AN Agres, SA Alves, D Höntzsch, R El Attal… - Gait & Posture, 2024 - Elsevier
Background Functional recovery after intramedullary nailing of distal tibial fractures can be
monitored using ipsilateral vertical ground reaction forces (vGRF), giving insight into …

Mechanical characterization via nanoindentation of the woven bone developed during bone transport

J Mora-Macías, A Pajares, P Miranda… - Journal of the …, 2017 - Elsevier
Nanoindentation has been used successfully in the determination of the mechanical
properties of bone. Its application in fracture healing provides information on the evolution of …

In vivo and in silico monitoring bone regeneration during distraction osteogenesis of the mouse femur

R Fu, D Bertrand, J Wang, K Kavaseri, Y Feng… - Computer Methods and …, 2022 - Elsevier
Background and objective Distraction osteogenesis (DO) is a mechanobiological process of
producing new bone by gradual and controlled distraction of the surgically separated bone …

Peri-implant cell differentiation in delayed and immediately-loaded dental implant: A mechanobiological simulation

M Babayi, MN Ashtiani, A Emamian… - Archives of Oral …, 2023 - Elsevier
Objective This study aimed to investigate the effect of immediate versus delayed dental
implant placement strategies on cell differentiation in a dental callus. Design The implant …

In Vivo Mechanical Characterization of the Distraction Callus During Bone Consolidation

J Mora-Macías, E Reina-Romo, M López-Pliego… - Annals of biomedical …, 2015 - Springer
Understanding the evolution of callus mechanical properties over time provides insights in
the mechanobiology of fracture healing and tissue differentiation, can be used to validate …