Historically, natural plant-derived drugs received a great impact of consideration in the
treatment of several human-associated disorders. Cancer is a devastating disease and the …

Sanguinarine is a quaternary ammonium benzophenanthine alkaloid found in traditional
herbs such as Chelidonium, Corydalis, Sanguinarum, and Borovula. It has been proven to …

Autophagy is an evolutionarily conserved self-degradation system that recycles cellular
components and damaged organelles, which is critical for the maintenance of cellular …

Although microglial activation is induced by an increase in chemokines, the role of
mitophagy in this process remains unclear. This study aimed to elucidate the role of …

Colorectal cancer (CRC) is a very common and deadly cancer worldwide, and oxaliplatin is
used as first‐line chemotherapy. However, resistance usually develops, limiting treatment …

Oxidative stress (OS) is linked to hepatocellular carcinoma (HCC) progression. HCC may
develop as a result of genetic changes, including oxidative injury to both nuclear and …

Abstract Background and Purpose Osteosarcoma, a primary malignant bone tumour
prevalent among adolescents and young adults, remains a considerable challenge despite …

Covering: 2019 to 2023 Isoquinoline alkaloids, an important class of N-based heterocyclic
compounds, have attracted considerable attention from researchers worldwide. To follow up …

Hepatocellular carcinoma (HCC), which is a primary liver cancer subtype, has a poor
prognosis due to its high degree of malignancy. The lack of early diagnosis makes systemic …

Bladder cancer (BC) is the most common cancer of the urinary tract, with poor survival, high
recurrence rates, and lacking of targeted drugs. In this study, we constructed a library to …