Clinical trials evaluating medicines, medical devices, and procedures now commonly
assess the economic value of these interventions. The growing number of prospective …

The use of modelling in economic evaluation is widespread, and it most often involves
synthesising data from a number of sources. However, even when economic evaluations are …

READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton,
Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society …

Decision‐making in health care is inevitably undertaken in a context of uncertainty
concerning the effectiveness and costs of health care interventions and programmes. One …

Cost‐effectiveness acceptability curves (CEACs) have been widely adopted as a method to
quantify and graphically represent uncertainty in economic evaluation studies of health‐care …

Cost-effectiveness analysis (CEA) is potentially an important aid to public health decision-
making but, with some notable exceptions, its use and impact at the level of individual …

Objectives: A growing number of prospective clinical trials include economic end points.
Recognizing the variation in methodology and reporting of these studies, the International …

OBJECTIVES: In this article, we describe how to include considerations about resource
utilization when making recommendations according to the Grading of Recommendations …

Use of cost-effectiveness acceptability curves, as a method for summarising information on
uncertainty cost-effectiveness, has become widespread within applied studies. This includes …

Objectives: To provide an overview of alternative approaches to modelling in economic
evaluation, and to highlight situations where each of the alternative modelling techniques …