Increasing evidence demonstrates that mechanical forces, in addition to soluble molecules,
impact cell and tissue functions in physiology and diseases. How living cells integrate …

Motor proteins such as myosin, kinesin, and dynein are essential to eukaryotic life and
power countless processes including muscle contraction, wound closure, cargo transport …

Human pancreatic cancer cell lines harbor a small population of tumor repopulating cells
(TRCs). Soft 3D fibrin gel allows efficient selection and growth of these tumorigenic TRCs …

A recently developed synthetic retinoid abrogates proliferation and induces apoptosis of
drug‐resistant malignant‐cancer‐stem‐cell‐like cells. However, the underlying mechanisms …

Soft 3D-fibrin-gel selected tumor repopulating cells (TRCs) from the B16F1 melanoma cell
line exhibit extraordinary self-renewal and tumor-regeneration capabilities. However, their …

Cell biologists have long aimed at quantitatively modeling cell function. Recently, the
outstanding progress of high-throughput measurement methods and data processing tools …

Abstract Changes in tissue architecture and multicellular organisation contribute to many
diseases, including cancer and cardiovascular diseases. Scratch wound assay is a …

Mechanotransduction of cells relies on responding to tension transmitted along various
supramolecular linkages. Tension gauge tethers (TGTs), short double-stranded DNA …

Relevance. The relevance of the study is conditioned by the need to form clear principles of
teaching medical biophysics to students, considering the main features of teaching biology …