Splitsville: structural and functional insights into the dynamic bacterial Z ring

DP Haeusser, W Margolin - Nature Reviews Microbiology, 2016 - nature.com
Bacteria must divide to increase in number and colonize their niche. Binary fission is the
most widespread means of bacterial cell division, but even this relatively simple mechanism …

The evolution of compositionally and functionally distinct actin filaments

PW Gunning, U Ghoshdastider… - Journal of cell …, 2015 - journals.biologists.com
The actin filament is astonishingly well conserved across a diverse set of eukaryotic species.
It has essentially remained unchanged in the billion years that separate yeast, Arabidopsis …

Genetic requirements for cell division in a genomically minimal cell

JF Pelletier, L Sun, KS Wise, N Assad-Garcia, BJ Karas… - Cell, 2021 - cell.com
Genomically minimal cells, such as JCVI-syn3. 0, offer a platform to clarify genes underlying
core physiological processes. Although this minimal cell includes genes essential for …

Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography

FR Wagner, R Watanabe, R Schampers, D Singh… - Nature protocols, 2020 - nature.com
Recent advances have made cryogenic (cryo) electron microscopy a key technique to
achieve near-atomic-resolution structures of biochemically isolated macromolecular …

The bacterial cell division proteins FtsA and FtsZ self-organize into dynamic cytoskeletal patterns

M Loose, TJ Mitchison - Nature cell biology, 2014 - nature.com
Bacterial cytokinesis is commonly initiated by the Z-ring, a cytoskeletal structure that
assembles at the site of division. Its primary component is FtsZ, a tubulin superfamily …

Assembly and activation of the Escherichia coli divisome

S Du, J Lutkenhaus - Molecular microbiology, 2017 - Wiley Online Library
Cell division in Escherichia coli is mediated by a large protein complex called the divisome.
Most of the divisome proteins have been identified, but how they assemble onto the Z ring …

The physiology of bacterial cell division

AJF Egan, W Vollmer - Annals of the New York Academy of …, 2013 - Wiley Online Library
Bacterial cell division is facilitated by the divisome, a dynamic multiprotein assembly
localizing at mid‐cell to synthesize the stress‐bearing peptidoglycan and to constrict all cell …

Architecture of the ring formed by the tubulin homologue FtsZ in bacterial cell division

P Szwedziak, Q Wang, TAM Bharat, M Tsim, J Löwe - Elife, 2014 - elifesciences.org
Membrane constriction is a prerequisite for cell division. The most common membrane
constriction system in prokaryotes is based on the tubulin homologue FtsZ, whose filaments …

FtsZ dynamics in bacterial division: What, how, and why?

JM Barrows, ED Goley - Current opinion in cell biology, 2021 - Elsevier
Bacterial cell division is orchestrated by the divisome, a protein complex centered on the
tubulin homolog FtsZ. FtsZ polymerizes into a dynamic ring that defines the division site …

Polysaccharide-capped silver Nanoparticles inhibit biofilm formation and eliminate multi-drug-resistant bacteria by disrupting bacterial cytoskeleton with reduced …

S Sanyasi, RK Majhi, S Kumar, M Mishra, A Ghosh… - Scientific reports, 2016 - nature.com
Abstract Development of effective anti-microbial therapeutics has been hindered by the
emergence of bacterial strains with multi-drug resistance and biofilm formation capabilities …