Simple Summary Skeletal muscle mass is an important economic trait, and muscle
development and growth is a crucial factor to supply enough meat for human consumption …

Cancer development depends on the aberrant activation of signal transduction pathways
that control cell growth and survival and play important roles in normal embryonic …

Chondrogenesis is a multistep process that is essential for endochondral bone formation.
Previous results have indicated a role for β-catenin and Wnt signaling in this pathway. Here …

Chronic obstructive pulmonary disease (COPD) is a debilitating disease characterized by
inflammation-induced airflow limitation and parenchymal destruction. In addition to …

Through their broad differentiation potential, mesenchymal stem cells (MSCs) are
candidates for a range of therapeutic applications, but the precise signaling pathways that …

Numerous cellular processes require the concerted action of multiple proteins that assemble
in functional complexes. Protein-protein interaction domains allow specific proteins to …

The differentiation of bone marrow mesenchymal stem cells (MSCs) into osteoblasts is a
crucial step in bone formation. However, the mechanisms involved in the early stages of …

In muscular dystrophies, muscle fibers loose integrity and die, causing significant suffering
and premature death. Strikingly, the extraocular muscles (EOMs) are spared, functioning …

The actin cytoskeleton is important for maintaining mechanical homeostasis in adherent
cells, largely through its regulation of adhesion and cortical tension. The LIM (L in‐11, I sl1 …

The four-and-a-half LIM (FHL) proteins belong to a family of LIM-only proteins that regulate
cell proliferation, differentiation, and apoptosis. The exact functions of each FHL protein in …