[HTML][HTML] Impact of per-and polyfluorinated alkyl substances (PFAS) on the marine environment: Raising awareness, challenges, legislation, and mitigation approaches …

LL Bilela, I Matijošytė, J Krutkevičius… - Marine pollution …, 2023 - Elsevier
Per-and polyfluorinated alkyl substances (PFAS) have long been known for their detrimental
effects on the ecosystems and living organisms; however the long-term impact on the marine …

A critical review on the bioaccumulation, transportation, and elimination of per-and polyfluoroalkyl substances in human beings

Y Lu, R Guan, N Zhu, J Hao, H Peng, A He… - Critical Reviews in …, 2024 - Taylor & Francis
Per-and polyfluoroalkyl substances (PFAS) have been manufactured for over seven
decades. Owing to the unique characteristics of CF bond, it has been widely used in the …

Structure-based investigation on the interaction of perfluorinated compounds with human liver fatty acid binding protein

L Zhang, XM Ren, LH Guo - Environmental science & technology, 2013 - ACS Publications
Perfluorinated compounds (PFCs) are known to accumulate in liver and induce
hepatotoxicity on experimental animals. Liver fatty acid binding protein (L-FABP) is …

Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice

SA Druzak, M Tardelli, SG Mays, M El Bejjani… - Nature …, 2023 - nature.com
Phosphatidylcholine transfer protein (PC-TP; synonym StarD2) is a soluble lipid-binding
protein that transports phosphatidylcholine (PC) between cellular membranes. To better …

Screening of potential PFOS alternatives to decrease liver bioaccumulation: experimental and computational approaches

H Cao, Z Zhou, L Wang, G Liu, Y Sun… - … science & technology, 2019 - ACS Publications
Perfluorooctanesulfonate (PFOS) is a persistent organic pollutant with significant
bioaccumulation potential in liver tissues. Exposure to PFOS could cause increase of liver …

FABP1 knockdown in human enterocytes impairs proliferation and alters lipid metabolism

LR Sawicki, NMB Arias, N Scaglia, LJF Lockhart… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Abstract Fatty Acid-Binding Proteins (FABPs) are abundant intracellular proteins that bind
long chain fatty acids (FA) and have been related with inmunometabolic diseases. Intestinal …

Fatty acid induced remodeling within the human liver fatty acid-binding protein

A Sharma, A Sharma - Journal of Biological Chemistry, 2011 - ASBMB
We crystallized human liver fatty acid-binding protein (LFABP) in apo, holo, and intermediate
states of palmitic acid engagement. Structural snapshots of fatty acid recognition, entry, and …

Effect of liver cancer on the accumulation and hepatobiliary transport of per-and polyfluoroalkyl substances

Y Liu, L Peng, Y Li, X Lu, F Wang, D Chen… - Journal of Hazardous …, 2024 - Elsevier
In this study, we examined the distribution of per-and polyfluoroalkyl substances (PFASs) in
liver and bile tissues from the patients with liver cancer (n= 202) and healthy controls (n …

Direct Interaction between EgFABP1, a Fatty Acid Binding Protein from Echinococcus granulosus, and Phospholipid Membranes

JL Porfido, G Alvite, V Silva, MW Kennedy… - PLoS neglected …, 2012 - journals.plos.org
Background Growth and maintenance of hydatid cysts produced by Echinococcus
granulosus have a high requirement for host lipids for biosynthetic processes, membrane …

Identification and characterization of the major pseudocoelomic proteins of the giant kidney worm, Dioctophyme renale

AN Giorello, MW Kennedy, MJ Butti, NE Radman… - Parasites & vectors, 2017 - Springer
Background The giant kidney worm, Dioctophyme renale, is a debilitating and potentially
lethal parasite that inhabits and destroys, typically host's right kidney, and may also be found …