New blood biomarkers for the diagnosis of AFP-negative hepatocellular carcinoma

T Wang, KH Zhang - Frontiers in Oncology, 2020 - frontiersin.org
An early diagnosis of hepatocellular carcinoma (HCC) followed by effective treatment is
currently critical for improving the prognosis and reducing the associated economic burden …

The role of hypoxia inducible factor‐1 in hepatocellular carcinoma

D Luo, Z Wang, J Wu, C Jiang… - BioMed research …, 2014 - Wiley Online Library
Hypoxia is a common feature of many solid tumors, including hepatocellular carcinoma
(HCC). Hypoxia can promote tumor progression and induce radiation and chemotherapy …

Disruption of PD-1 enhanced the anti-tumor activity of chimeric antigen receptor T cells against hepatocellular carcinoma

X Guo, H Jiang, B Shi, M Zhou, H Zhang… - Frontiers in …, 2018 - frontiersin.org
Cancer immunotherapy has made unprecedented breakthrough in the fields of chimeric
antigen receptor-redirected T (CAR T) cell therapy and immune modulation. Combination of …

MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches

E Callegari, L Gramantieri, M Domenicali… - Cell Death & …, 2015 - nature.com
MicroRNAs (miRNAs) constitute a large class of short RNAs (eg, 20–24 nucleotides in
length), whose main function is to posttranscriptionally regulate the expression of protein …

MicroRNA profile in HBV-induced infection and hepatocellular carcinoma

G Wang, F Dong, Z Xu, S Sharma, X Hu, D Chen… - BMC cancer, 2017 - Springer
Background MicroRNAs (miRNAs) exhibit essential regulatory functions related to cell
growth, apoptosis, development and differentiation. Dysregulated expression of miRNAs is …

[HTML][HTML] MiR-497 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting VEGFA and AEG-1

JJ Yan, YN Zhang, JZ Liao, K Ke, Y Chang, PY Li… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a worldwide malignance and displays marked vascular
abnormalities and active metastasis. MicroRNAs (miRNAs) have been shown to play …

[HTML][HTML] Epigenetics in hepatocellular carcinoma: an update and future therapy perspectives

L Ma, MS Chua, O Andrisani, S So - World Journal of …, 2014 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), the predominant form of adult liver malignancies, is a
global health concern. Its dismal prognosis has prompted recent significant advances in the …

Targeted delivery of microRNA‐199a‐3p using self‐assembled dipeptide nanoparticles efficiently reduces hepatocellular carcinoma in mice

A Varshney, JJ Panda, AK Singh, N Yadav… - …, 2018 - Wiley Online Library
Hepatocellular carcinoma (HCC) is an aggressive tumor with limited systemic and
locoregional modalities of treatment. Although microRNA (miRNA) based therapies have …

MicroRNAs involved with hepatocellular carcinoma

B Mao, G Wang - Oncology Reports, 2015 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common malignancies, which accounts
for 90% of primary liver cancer. HCC usually presents with poor outcomes due to the high …

Association of serum microRNA expression in hepatocellular carcinomas treated with transarterial chemoembolization and patient survival

M Liu, J Liu, L Wang, H Wu, C Zhou, H Zhu, N Xu… - PloS one, 2014 - journals.plos.org
Background and Aim Hepatocellular carcinoma (HCC) is one of the most deadly tumors.
Transarterial chemoembolization (TACE) is effective for unresectable HCC. In recent years …