Anti-inflammatory peptide therapeutics and the role of sulphur containing amino acids (cysteine and methionine) in inflammation suppression: A review

CA Biji, A Balde, RA Nazeer - Inflammation Research, 2024 - Springer
Background Inflammation serves as our body's immune response to combat infections,
pathogens, viruses, and external stimuli. Inflammation can be classified into two types: acute …

Evidence‐based dietary management of inflammatory bowel disease

PR Gibson, CK Yao, EP Halmos - Alimentary Pharmacology & …, 2024 - Wiley Online Library
Background Dietary management of patients with inflammatory bowel disease (IBD)
involves more than defining a therapeutic diet. The profusion of 'expert advice'is not …

Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre …

MC Choy, CFDLW Suen, D Con, K Boyd… - The Lancet …, 2024 - thelancet.com
Background The optimal dosing strategy for infliximab in steroid-refractory acute severe
ulcerative colitis (ASUC) is unknown. We compared intensified and standard dose infliximab …

Diagnosis and management of inflammatory bowel disease

L Li, R Cheng, Y Wu, H Lin, H Gan… - Journal of Evidence …, 2024 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic and relapsing immune‐mediated disease of
the gastrointestinal tract with a gradually increasing global incidence and prevalence. A …

Optimisation of biologic (monoclonal antibody) therapeutic response in inflammatory bowel disease

T Chaemsupaphan, RW Leong… - Alimentary …, 2024 - Wiley Online Library
Background There are a plethora of therapeutic options for the management of inflammatory
bowel disease (IBD). Despite this, clinical outcomes with standard dosing often fall short of …

Immunogenicity of Therapeutic Antibodies Used for Inflammatory Bowel Disease: Treatment and Clinical Considerations

OH Nielsen, A Hammerhøj, MA Ainsworth, J Gubatan… - Drugs, 2024 - Springer
The introduction of tumor necrosis factor inhibitors has led to a paradigm shift in the
management of inflammatory bowel disease (IBD). The subsequent introduction of both anti …

Small molecules, big results: how JAK inhibitors have transformed the treatment of patients with IBD

K Fansiwala, JS Sauk - Digestive Diseases and Sciences, 2024 - Springer
Small molecule Janus kinase (JAK) inhibitors have revolutionized the management of
ulcerative colitis (UC) and Crohn's disease (CD) through their low immunogenicity, safety …

Therapeutic drug monitoring in inflammatory bowel disease: recent developments

X Roblin, RD Little, N Mathieu, S Paul… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Therapeutic Drug Monitoring (TDM) has an important role in the
management of inflammatory bowel disease (IBD) patients on infliximab (IFX) or …

[HTML][HTML] Current Status, Challenges, and Future Directions in Crohn's Disease

C Selinger, A van der Meulen - Journal of Clinical Medicine, 2024 - mdpi.com
The treatment goal for patients with Crohn's disease (CD) has traditionally been aimed at
symptomatic steroid-free clinical remission [1]. Mucosal healing, endoscopic healing, and …

Overcoming the challenges of overtreating and undertreating inflammatory bowel disease

MJ Temido, S Honap, V Jairath, S Vermeire… - The Lancet …, 2025 - thelancet.com
Several therapeutic advances have been achieved over the past two decades for
inflammatory bowel disease (IBD). The expanding therapeutic armamentarium and the …