Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches

C Mutuku, Z Gazdag, S Melegh - World Journal of Microbiology and …, 2022 - Springer
Antimicrobial pharmaceuticals are classified as emergent micropollutants of concern,
implying that even at low concentrations, long-term exposure to the environment can have …

Dissemination of antimicrobial resistance in microbial ecosystems through horizontal gene transfer

CJH Von Wintersdorff, J Penders… - Frontiers in …, 2016 - frontiersin.org
The emergence and spread of antibiotic resistance among pathogenic bacteria has been a
rising problem for public health in recent decades. It is becoming increasingly recognized …

Fitness costs of plasmids: a limit to plasmid transmission

A San Millan, RC MacLean - Microbiology spectrum, 2017 - Am Soc Microbiol
Plasmids mediate the horizontal transmission of genetic information between bacteria,
facilitating their adaptation to multiple environmental conditions. An especially important …

[HTML][HTML] Small-scale wastewater treatment plants as a source of the dissemination of antibiotic resistance genes in the aquatic environment

A Osińska, E Korzeniewska, M Harnisz, E Felis… - Journal of hazardous …, 2020 - Elsevier
Wastewater treatment plants (WWTPs) are significant source of antibiotic resistant bacteria
(ARB) and antibiotic resistance genes (ARGs), which can spread further in the environment …

Integrative and conjugative elements (ICEs): what they do and how they work

CM Johnson, AD Grossman - Annual review of genetics, 2015 - annualreviews.org
Horizontal gene transfer plays a major role in microbial evolution, allowing microbes to
acquire new genes and phenotypes. Integrative and conjugative elements (ICEs, aka …

Acquired antibiotic resistance genes: an overview

AHAM Van Hoek, D Mevius, B Guerra… - Frontiers in …, 2011 - frontiersin.org
In this review an overview is given on antibiotic resistance (AR) mechanisms with special
attentions to the AR genes described so far preceded by a short introduction on the …

The role of integrative and conjugative elements in antibiotic resistance evolution

J Botelho, H Schulenburg - Trends in microbiology, 2021 - cell.com
Mobile genetic elements (MGEs), such as plasmids and integrative and conjugative
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution …

Environmental dissemination of antibiotic resistance genes and correlation to anthropogenic contamination with antibiotics

B Berglund - Infection ecology & epidemiology, 2015 - Taylor & Francis
Antibiotic resistance is a growing problem which threatens modern healthcare globally.
Resistance has traditionally been viewed as a clinical problem, but recently non-clinical …

Horizontal gene exchange in environmental microbiota

RI Aminov - Frontiers in microbiology, 2011 - frontiersin.org
Horizontal gene transfer (HGT) plays an important role in the evolution of life on the Earth.
This view is supported by numerous occasions of HGT that are recorded in the genomes of …

Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow

RAF Wozniak, MK Waldor - Nature Reviews Microbiology, 2010 - nature.com
Integrative and conjugative elements (ICEs) are a diverse group of mobile genetic elements
found in both Gram-positive and Gram-negative bacteria. These elements primarily reside in …