The Plasmodium parasite, the causative agent of malaria, is an excellent model for
immunomic-based approaches to vaccine development. The Plasmodium parasite has a …

Vector-borne diseases constitute an enormous burden on public health across the world.
However, despite the importance of interactions between infectious pathogens and their …

The apicomplexan order Haemosporida is a clade of unicellular blood parasites that infect a
variety of reptilian, avian and mammalian hosts. Among them are the agents of human …

RNA interference (RNAi) is an RNA degradation process that involves short, double-
stranded RNAs (dsRNA) as sequence specificity factors. The natural function of the RNAi …

Malaria remains a major global health problem and cerebral malaria (CM) is one of the most
serious complications of this disease. Recent years have seen important advances in our …

Throughout the Plasmodium life cycle, malaria parasites repeatedly undergo rapid cellular
growth and prolific divisions, necessitating intense membrane neogenesis and, in particular …

The sexual phase of the malaria parasite Plasmodium falciparum is essential for
transmission of the disease and is accompanied by the co-ordinated expression of sexual …

Vaccines are one of the most effective interventions to improve public health, however, the
generation of highly effective vaccines for many diseases has remained difficult. Three …

Malaria kills more than a million people a year, causes malady in about three hundred
million people and poses risk to approximately 40% of the world's population living in …

Invasion of hepatocytes by Plasmodium sporozoites is a prerequisite for establishment of a
natural malaria infection. The molecular mechanisms underlying sporozoite invasion are …