Abstract The IL-6/JAK/STAT3 pathway is aberrantly hyperactivated in many types of cancer,
and such hyperactivation is generally associated with a poor clinical prognosis. In the …

Infections represent a common health problem in people of all ages. Usually, the response
given to them is appropriate and so little treatment is needed. Sometimes, however, the …

Background & aims Malnutrition has been recognized as a major risk factor for adverse
postoperative outcomes. The ESPEN Symposium on perioperative nutrition was held in …

Introduction Cancer remains a leading cause of death worldwide. While a curative intent is
the aim of any surgical treatment many patients either present with or go onto develop …

The magnitude, invasiveness, and duration of surgery are central in determining the degree
of the body's integrated stress response. Major open vascular and abdominal surgery, joint …

Observational data have shown that some cancer survivors develop chronic conditions like
frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at a …

In some patients, the inflammatory‐immune response to surgical injury progresses to a
harmful, dysregulated state. We posit that postoperative systemic inflammatory dysregulation …

Objective This study was designed to estimate the clinical significance of the C-reactive
protein (CRP)/albumin ratio (CAR) for prediction of postoperative survival in patients with …

We present a narrative review focusing on the new role of nociception monitor in
intraoperative anesthetic management. Higher invasiveness of surgery elicits a higher …

One percent to 2% of pregnant women undergo nonobstetric surgery during pregnancy.
Historically, there has been a reluctance to operate on pregnant women based on concerns …