Platforms, advances, and technical challenges in virus-like particles-based vaccines

R Gupta, K Arora, SS Roy, A Joseph… - Frontiers in …, 2023 - frontiersin.org
Viral infectious diseases threaten human health and global stability. Several vaccine
platforms, such as DNA, mRNA, recombinant viral vectors, and virus-like particle-based …

COVID-19 vaccines: current and future perspectives

L Soraci, F Lattanzio, G Soraci, ME Gambuzza… - Vaccines, 2022 - mdpi.com
Currently available vaccines against severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) are highly effective but not able to keep the coronavirus disease 2019 …

Electrostatic features for the receptor binding domain of SARS-COV-2 wildtype and its variants. Compass to the severity of the future variants with the charge-rule

FL Barroso da Silva, CC Giron… - The Journal of Physical …, 2022 - ACS Publications
Electrostatic intermolecular interactions are important in many aspects of biology. We have
studied the main electrostatic features involved in the interaction of the receptor-binding …

An overview of current drugs and prophylactic vaccines for coronavirus disease 2019 (COVID-19)

A Alagheband Bahrami, A Azargoonjahromi… - Cellular & molecular …, 2022 - Springer
Designing and producing an effective vaccine is the best possible way to reduce the burden
and spread of a disease. During the coronavirus disease 2019 (COVID-19) pandemic, many …

[HTML][HTML] Nanocarrier vaccine therapeutics for global infectious and chronic diseases

FZ Simnani, D Singh, P Patel, A Choudhury, A Sinha… - Materials Today, 2023 - Elsevier
Immunization has the potential to become a viable weapon for the upcoming pandemic and
save millions of lives, while also dramatically lowering the high mortality rate brought on by a …

Exigency of Plant-Based Vaccine against COVID-19 Emergence as Pandemic Preparedness

A Chattopadhyay, AAK Jailani, B Mandal - Vaccines, 2023 - mdpi.com
After two years since the declaration of COVID-19 as a pandemic by the World Health
Organization (WHO), more than six million deaths have occurred due to SARS-CoV-2 …

Harnessing nanovaccines for effective immunization─ a special concern on COVID-19: facts, fidelity, and future prospective

AD Gholap, J Gupta, P Kamandar… - ACS biomaterials …, 2023 - ACS Publications
Nanotechnology has emerged as a transformative pathway in vaccine research and
delivery. Nanovaccines, encompassing lipid and nonlipid formulations, exhibit considerable …

Photodynamic viral inactivation assisted by photosensitizers

M Sadraeian, L Zhang, F Aavani, E Biazar, D ** - Materials Today Physics, 2022 - Elsevier
The deadly viruses, which are spreading worldwide at an alarming rate, are a major
challenge for the life sciences. More efficient and cost-effective methods with fewer side …

[HTML][HTML] Viral protein-based nanoparticles (part 2): Pharmaceutical applications

R Mellid-Carballal, S Gutierrez-Gutierrez… - European Journal of …, 2023 - Elsevier
ABSTRACT Viral protein nanoparticles (ViP NPs) such as virus-like particles and virosomes
are structures halfway between viruses and synthetic nanoparticles. The biological nature of …

Characterization of extracellular vesicle and virus-like particles by single vesicle tetraspanin analysis

C Han, M Kang, H Kang, J Yi, M Lim, Y Kwon… - Sensors and Actuators B …, 2023 - Elsevier
Extracellular vesicles (EVs) are nano-sized membranous particles secreted by cells. EVs
have been classified into subpopulations according to their presumed biogenesis pathway …