Abstract Protein–protein interactions (PPIs), such as protein–protein inhibitor, antibody–
antigen complex, and supercomplexes play diverse and important roles in cells. Recent …

The past century has witnessed an exponential increase in our atomic-level understanding
of molecular and cellular mechanisms from a structural perspective, with multiple landmark …

AlphaFold2 and RoseTTAFold predict protein structures with very high accuracy despite
substantial architecture differences. We sought to develop an improved method combining …

Symmetry in nature often emerges from self-assembly processes and serves a wide range of
functions. Cell surface layers (S-layers) form symmetrical lattices on many bacterial and …

The performance of deep Neural Networks (NNs) in the text (ChatGPT) and image (DALL‐
E2) domains has attracted worldwide attention. Convolutional NNs (CNNs), Large …

The majority of proteins must form higher-order assemblies to perform their biological
functions. Despite the importance of protein quaternary structure, there are few machine …