The centromere is a chromosomal locus responsible for the faithful segregation of genetic
material during cell division. It has become evident that centromeres can be established …

A considerable fraction of the eukaryotic genome is made up of satellite DNA constituted of
tandemly repeated sequences. These elements are mainly located at centromeres …

Background The soil transmitted helminths are a group of parasitic worms responsible for
extensive morbidity in many of the world's most economically depressed locations. With …

Transposable elements (TEs) and satellite DNAs (satDNAs) are typically identified as major
repetitive DNA components in eukaryotic genomes. TEs are DNA segments able to move …

Since their discovery more than 60 years ago, satellite repeats are still one of the most
enigmatic parts of eukaryotic genomes. Being non-coding DNA, satellites were earlier …

The centromere is the nucleoproteic chromosomal structure necessary for accurate
chromosome segregation during cell division. One of the earliest centromeric proteins to be …

Eukaryotic genomes are rich in repetitive DNA sequences grouped in two classes regarding
their genomic organization: tandem repeats and dispersed repeats. In tandem repeats …

The true importance of cell-free DNA in human biology, together with the potential scale of
its clinical utility, is tarnished by a lack of understanding of its composition and origin. In …

Although circulating DNA (cirDNA) analysis shows great promise as a screening tool for a
wide range of pathologies, numerous stumbling blocks hinder the rapid translation of …

Abstract Background Satellite DNA (satDNA) sequences are typically arranged as arrays of
tandemly repeated monomers. Due to the similarity among monomers, their organizational …