Inflammation: mechanisms, costs, and natural variation
Inflammation is a pervasive phenomenon that operates during severe perturbations of
homeostasis, such as infection, injury, and exposure to contaminants, and is triggered by …
homeostasis, such as infection, injury, and exposure to contaminants, and is triggered by …
Tolerance of infections
JS Ayres, DS Schneider - Annual review of immunology, 2012 - annualreviews.org
A host has two methods to defend against pathogens: It can clear the pathogens or reduce
their impact on health in other ways. The first, resistance, is well studied. Study of the …
their impact on health in other ways. The first, resistance, is well studied. Study of the …
On the relationship between body condition and parasite infection in wildlife: a review and meta‐analysis
Body condition metrics are widely used to infer animal health and to assess costs of parasite
infection. Since parasites harm their hosts, ecologists might expect negative relationships …
infection. Since parasites harm their hosts, ecologists might expect negative relationships …
Disease ecology meets ecological immunology: understanding the links between organismal immunity and infection dynamics in natural populations
Ecological immunology and disease ecology are two relatively young disciplines that apply
ecological approaches and principles to traditionally non‐ecological fields. In both cases, an …
ecological approaches and principles to traditionally non‐ecological fields. In both cases, an …
Macroimmunology: The drivers and consequences of spatial patterns in wildlife immune defence
The prevalence and intensity of parasites in wild hosts varies across space and is a key
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …
Physiological mechanisms mediating costs of immune responses: what can we learn from studies of birds?
Activating the immune system has associated fitness costs, both immediate costs in the form
of reduced current reproduction and long-term costs in the form of reduced life span and …
of reduced current reproduction and long-term costs in the form of reduced life span and …
Wild immunology
In wild populations, individuals are regularly exposed to a wide range of pathogens. In this
context, organisms must elicit and regulate effective immune responses to protect their …
context, organisms must elicit and regulate effective immune responses to protect their …
An ecosystem approach to understanding and managing within-host parasite community dynamics
Hosts are typically coinfected by multiple parasite species, resulting in potentially
overwhelming levels of complexity. We argue that an individual host can be considered to …
overwhelming levels of complexity. We argue that an individual host can be considered to …
[HTML][HTML] Maximising fitness in the face of parasites: a review of host tolerance
Tolerance, the ability of a host to limit the negative fitness effects of a given parasite load, is
now recognised as an important host defence strategy in animals. Together with resistance …
now recognised as an important host defence strategy in animals. Together with resistance …
How behavioural ageing affects infectious disease
Ageing is associated with profound changes in behaviour that could influence exposure and
susceptibility to infectious disease. As well as determining emergent patterns of infection …
susceptibility to infectious disease. As well as determining emergent patterns of infection …