Click Chemistry for Biofunctional Polymers: From Observing to Steering Cell Behavior

K Ghosal, SK Bhattacharyya, V Mishra… - Chemical …, 2024 - ACS Publications
Click chemistry has become one of the most powerful construction tools in the field of
organic chemistry, materials science, and polymer science, as it offers hassle-free platforms …

[HTML][HTML] Recent advances in zwitterionic nanoscale drug delivery systems to overcome biological barriers

X Ouyang, Y Liu, K Zheng, Z Pang, S Peng - Asian journal of …, 2024 - Elsevier
Nanoscale drug delivery systems (nDDS) have been employed widely in enhancing the
therapeutic efficacy of drugs against diseases with reduced side effects. Although several …

Opsonization Inveigles Macrophages Engulfing Carrier‐Free Bilirubin/JPH203 Nanoparticles to Suppress Inflammation for Osteoarthritis Therapy

H Huang, S Zheng, J Wu, X Liang, S Li… - Advanced …, 2024 - Wiley Online Library
Osteoarthritis (OA) is a chronic inflammatory disease characterized by cartilage destruction,
synovitis, and osteophyte formation. Disease‐modifying treatments for OA are currently …

Fast-polymerized lubricant and antibacterial hydrogel coatings for medical catheters

C Sun, Y Zhang, F Dong, J Zhao, P Zhang, S Li… - Chemical Engineering …, 2024 - Elsevier
Medical catheters are highly susceptible to friction and infection when intervening or
implanting in the body, and to thrombosis when in contact with blood. Coating medical …

Nanomedicines promote cartilage regeneration in osteoarthritis by synergistically enhancing chondrogenesis of mesenchymal stem cells and regulating inflammatory …

SH Cui, Y Yan, A Lu, Y Dou, ZW Li, ZH Zhu, MZ Du… - ACS …, 2024 - ACS Publications
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of
the articular cartilage and inflammation. Mesenchymal stem cells'(MSCs) transplantation in …

Supramolecular 3 in 1: A Lubrication and Co-Delivery System for Synergistic Advanced Osteoarthritis Therapy

MM Chen, Y Li, Y Zhu, WC Geng, FY Chen, JJ Li… - ACS …, 2024 - ACS Publications
The complexity, heterogeneity, and drug resistance of diseases necessitate a shift in
therapeutic paradigms from monotherapy to combination therapy, which could augment …

Curcumin-loaded macrophage-derived exosomes effectively improve wound healing

D Li, C Zhang, Z Gao, N **a, C Wu, C Liu… - Molecular …, 2023 - ACS Publications
This study aims to investigate the potential therapeutic effect of exosomes derived from
macrophages loaded with curcumin (Exos-cur) on the healing of diabetic wounds. As a new …

Intra‐Articular Injection of Nanomaterials for the Treatment of Osteoarthritis: From Lubrication Function Restoration to Cell and Gene Therapy

Y Yang, H Zhang - Advanced Functional Materials, 2024 - Wiley Online Library
Osteoarthritis (OA), a prevalent joint disease affecting many people globally, presents
significant challenge in current treatments, which often only manage symptoms without …

A Dual Functional Bioinspired Lubricant for Osteoarthritis Treatment and Potential Prevention

R Yan, H Yang, Y Liu, Y Wang, S Liu… - ACS applied materials …, 2024 - ACS Publications
Osteoarthritis (OA), primarily characterized by the deterioration of articular cartilage, is a
highly prevalent joint-disabling disease. The pathological onset and progression of OA are …

Biomimetic zwitterionic copolymerized chitosan as an articular lubricant

J Deng, R Wei, H Qiu, X Wu, Y Yang, Z Huang… - Carbohydrate …, 2024 - Elsevier
Restoration of the lubrication functions of articular cartilage is an effective treatment to
alleviate the progression of osteoarthritis (OA). Herein, we fabricated chitosan-block-poly …