Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …

Cancer-derived extracellular vesicles (EVs) are membrane-enclosed structures of highly
variable size. EVs contain a myriad of substances (proteins, lipid, RNA, DNA) that provide a …

Exosomes are extracellular signalosomes that facilitate eukaryotic intercellular
communication under a wide range of normal physiological contexts. In malignancies, this …

The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

Exosomes are nano-sized membrane vesicles released by a variety of cell types, and are
thought to play important roles in intercellular communications. In breast cancer, through …

Extracellular vesicles have the capacity to transfer lipids, proteins, and nucleic acids
between cells, thereby influencing the recipient cell's phenotype. While the role of RNAs in …

For studying cellular communications ex-vivo, a two-dimensional (2D) cell culture model is
currently used as the “gold standard”. 2D culture models are also widely used in the study of …

Improved treatment of breast cancer, the world's second most common cancer, requires
identification of new sensitive prognostic and diagnostic biomarkers. Exosomes are lipid …

Tumor-derived exosomes contain biologically active proteins and messenger and
microRNAs (miRNAs). These particles serve as vehicles of intercellular communication and …