Data-independent acquisition (DIA) mass spectrometry (MS) has emerged as a powerful
technology for high-throughput, accurate, and reproducible quantitative proteomics. This …

Precision cancer medicine is a multidisciplinary team effort that requires involvement and
commitment of many stakeholders including the society at large. Building on the success of …

Liquid chromatography (LC) coupled with data-independent acquisition (DIA) mass
spectrometry (MS) has been increasingly used in quantitative proteomics studies. Here, we …

Peptide identification in liquid chromatography-tandem mass spectrometry (LC-MS/MS)
experiments relies on computational algorithms for matching acquired MS/MS spectra …

In the medical, environmental, and biotechnological fields, microbial communities have
attracted much attention due to their roles and numerous possible applications. The study of …

The FragPipe computational proteomics platform is gaining widespread popularity among
the proteomics research community because of its fast processing speed and user-friendly …

The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

Mass spectrometry (MS)-based blood proteomics is a crucial research focus in identifying
disease biomarkers. Blood serum or plasma is the most commonly used sample for such …

Thermal proteome profiling (TPP) provides a powerful approach to studying proteome-wide
interactions of small therapeutic molecules and their target and off-target proteins …

Data-independent acquisition (DIA) approaches provide comprehensive records of all
detectable pre-cursor and fragment ions. Here we introduce midiaPASEF, a novel DIA scan …