The RhoGTPases, with RhoA, Cdc42 and Rac being major members, are a group of key
ubiquitous proteins present in all eukaryotic organisms that subserve such important …

Among the seventeen species of the Gram-negative genus Yersinia, three have been shown
to be virulent and pathogenic to humans and animals—Y. enterocolitica, Y …

The recent and dramatic rise of antibiotic resistance among bacterial pathogens underlies
the fear that standard treatments for infectious disease will soon be largely ineffective …

Bartonella spp. are facultative intracellular bacteria that typically cause a long-lasting
intraerythrocytic bacteremia in their mammalian reservoir hosts, thereby favoring …

Yersinia (Y.) enterocolitica, an etiological agent of yersiniosis, is a bacterium whose
pathogenicity is determined, among other things, by its ability to produce toxins. The aim of …

Yersinia pestis, the etiologic agent of plague, utilizes a type III secretion system (T3SS) to
subvert the defenses of its mammalian hosts. T3SSs are complex nanomachines that allow …

Intimin and invasin are adhesins and central virulence factors of attaching and effacing
bacteria, such as enterohaemorrhagic Escherichia coli, and enteropathogenic Yersiniae …

Highlights•Cell surface components mediate resistance of Yersinia to extracellular immune
factors.•Interaction between Yersinia and host cells promotes dissemination and drives …

Yersinia pseudotuberculosis is an Enterobacteriaceae family member that is commonly
transmitted by the fecal-oral route to cause infections. From the small intestine, Y …

Trimeric autotransporter adhesins (TAAs) on the cell surface of Gram-negative pathogens
mediate bacterial adhesion to host cells and extracellular matrix proteins. However, AtaA, a …