A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments

T Qian, H Wang, P Wang, L Geng, L Mei… - Nature …, 2023‏ - nature.com
Oxytocin (OT), a peptide hormone and neuromodulator, is involved in diverse physiological
and pathophysiological processes in the central nervous system and the periphery …

Dorsal hippocampus to nucleus accumbens projections drive reinforcement via activation of accumbal dynorphin neurons

KM Ibrahim, N Massaly, HJ Yoon, R Sandoval… - Nature …, 2024‏ - nature.com
The hippocampus is pivotal in integrating emotional processing, learning, memory, and
reward-related behaviors. The dorsal hippocampus (dHPC) is particularly crucial for …

Social buffering in rats reduces fear by oxytocin triggering sustained changes in central amygdala neuronal activity

C Hegoburu, Y Tang, R Niu, S Ghosh… - Nature …, 2024‏ - nature.com
The presence of a companion can reduce fear, but the neural mechanisms underlying this
social buffering of fear are incompletely known. We studied social buffering of fear in male …

Compartmental neuropeptide release measured using a new oxytocin sensor

T Qian, H Wang, P Wang, L Geng, L Mei, T Osakada… - BioRxiv, 2022‏ - biorxiv.org
As a peptide hormone and neuromodulator, oxytocin (OT) plays a critical role in a variety of
physiological and pathophysiological processes in both the central nervous system and the …

Oxytocin in lactation and parturition

G Leng - … Regulation of Mammalian Pregnancy and Lactation, 2024‏ - Springer
This chapter outlines the physiology of the oxytocin system as relevant to our understanding
of the milk-ejection reflex, and of the control of parturition, as developed through …

[HTML][HTML] Protocol for in vivo dual-color fiber photometry in the mouse thalamus

A Serikov, I Martsishevska, W Shin, J Kim - STAR protocols, 2024‏ - Elsevier
In vivo calcium imaging of neural activity is an indispensable approach for understanding
the mechanisms and functions of neural system. Development of advanced imaging tools …

The Relationship Between Oxytocin and Alcohol Dependence

J Schimmer, R Patwell, S Küppers, V Grinevich - 2023‏ - Springer
The hypothalamic neuropeptide oxytocin (OT) is well known for its prosocial, anxiolytic, and
ameliorating effects on various psychiatric conditions, including alcohol use disorder (AUD) …

A novel analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray

M Iwasaki, A Lefevre, F Althammer, O Łąpieś, L Hilfiger… - BioRxiv, 2022‏ - biorxiv.org
The hypothalamic neuropeptide, oxytocin (OT), exerts prominent analgesic effects via
central and peripheral action. Here we discovered a novel subset of OT neurons whose …

[HTML][HTML] Calcium imaging and BAPTA loading of amygdala astrocytes in mouse brain slices

A Baudon, E Clauss-Creusot, P Darbon, R Patwell… - STAR protocols, 2022‏ - Elsevier
Astrocytes are glial cells that exhibit calcium signaling-mediated activity. Here, we present a
protocol to monitor and manipulate astrocyte calcium activity from mouse amygdala slices. In …

Effects of bile duct ligation on the inhibitory control of supraoptic vasopressin neurons

AO Aikins, GE Farmer, JT Little… - Journal of …, 2023‏ - Wiley Online Library
Dilutional hyponatremia due to increased plasma arginine vasopressin (AVP) is associated
with liver cirrhosis. However, plasma AVP remains elevated despite progressive …