Microwave heating in solid-phase peptide synthesis

SL Pedersen, AP Tofteng, L Malik… - Chemical Society …, 2012 - pubs.rsc.org
The highly refined organic chemistry in solid-phase synthesis has made it the method of
choice not only to assemble peptides but also small proteins–mainly on a laboratory scale …

Controlled microwave heating in modern organic synthesis: highlights from the 2004–2008 literature

CO Kappe, D Dallinger - Molecular diversity, 2009 - Springer
Direct and rapid heating by microwave irradiation in combination with sealed vessel
processing in many cases enables reactions to be carried out in a fraction of the time …

A critical assessment of the greenness and energy efficiency of microwave-assisted organic synthesis

JD Moseley, CO Kappe - Green Chemistry, 2011 - pubs.rsc.org
The question “why should microwave chemistry be green?” is evaluated in the context of the
twelve principles of green chemistry, with a focus on the 6th principle: design for energy …

[LIVRE][B] Microwave heating as a tool for sustainable chemistry

NE Leadbeater - 2010 - taylorfrancis.com
Shorter reaction times, higher product yields, and enhanced selectivity are some of the
advantages microwave heating has over conventional methods, causing its use to transition …

Understanding microwave heating effects in single mode type cavities—theory and experiment

J Robinson, S Kingman, D Irvine, P Licence… - Physical Chemistry …, 2010 - pubs.rsc.org
This paper explains the phenomena which occur in commercially available laboratory
microwave equipment, and highlights several situations where experimental observations …

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

MM Fabani, C Abreu-Goodger, D Williams… - Nucleic acids …, 2010 - academic.oup.com
MicroRNAs (miRNAs) play an important role in diverse physiological processes and are
potential therapeutic agents. Synthetic oligonucleotides (ONs) of different chemistries have …

Solid-phase synthesis of difficult peptide sequences at elevated temperatures: a critical comparison of microwave and conventional heating technologies

B Bacsa, K Horvati, S Bosze, F Andreae… - The Journal of organic …, 2008 - ACS Publications
The Fmoc/t-Bu solid-phase synthesis of three difficult peptide sequences (a 9-mer, 15-mer,
and 24-mer) was performed using N, N′-diisopropylcarbodiimide/1-hydroxybenzotriazole …

Energy efficiency of heterogeneous catalytic microwave-assisted organic reactions

H Cho, F Török, B Török - Green Chemistry, 2014 - pubs.rsc.org
The energy efficiency of microwave-assisted reactions was studied under heterogeneous
catalytic conditions. Based on earlier publications the choice of catalyst was a semi-synthetic …

Transport phenomena in solid phase synthesis supported by cross-linked polymer beads

S Pinzón-López, M Kraume… - Reaction Chemistry & …, 2023 - pubs.rsc.org
Solid Phase Synthesis (SPS) is a powerful tool for synthesizing oligomers, especially
peptides, nucleic acids, and glycans. Since Merrifield developed solid-phase peptide …

Nickel–PNN catalysed sustainable synthesis of polysubstituted quinolines under microwave irradiation

MA Mohite, S Sheokand… - Catalysis Science & …, 2024 - pubs.rsc.org
In this manuscript, the synthesis of a series of cationic NiII complexes based on mixed donor
triazolyl-pyridine-based aminophosphine,[(NiCl){R′ PRNN}-κ3-P, N, N] OTf (R= H or Me; …