Type 2 immunity in the skin and lungs

CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

The pathogenesis of giant condyloma acuminatum (Buschke-Lowenstein tumor): an overview

D Purzycka-Bohdan, RJ Nowicki, F Herms… - International Journal of …, 2022 - mdpi.com
Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor (BLT), is a rare
disease of the anogenital region. BLT is considered a locally aggressive tumor of benign …

Human inborn errors of immunity: 2019 update on the classification from the International Union of Immunological Societies Expert Committee

SG Tangye, W Al-Herz, A Bousfiha, T Chatila… - Journal of clinical …, 2020 - Springer
We report the updated classification of Inborn Errors of Immunity/Primary
Immunodeficiencies, compiled by the International Union of Immunological Societies Expert …

Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes

J Hadjadj, N Aladjidi, H Fernandes… - Blood, The Journal …, 2019 - ashpublications.org
Evans syndrome (ES) is a rare severe autoimmune disorder characterized by the
combination of autoimmune hemolytic anemia and immune thrombocytopenia. In most …

An integrated taxonomy for monogenic inflammatory bowel disease

C Bolton, CS Smillie, S Pandey, R Elmentaite, G Wei… - Gastroenterology, 2022 - Elsevier
Background & aims Monogenic forms of inflammatory bowel disease (IBD) illustrate the
essential roles of individual genes in pathways and networks safeguarding immune …

Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity

G Sogkas, F Atschekzei, IR Adriawan… - Cellular & Molecular …, 2021 - nature.com
In addition to susceptibility to infections, conventional primary immunodeficiency disorders
(PIDs) and inborn errors of immunity (IEI) can cause immune dysregulation, manifesting as …

[HTML][HTML] Skin barrier immunology from early life to adulthood

A Trompette, ND Ubags - Mucosal Immunology, 2023 - Elsevier
Our skin has a unique barrier function, which is imperative for the body's protection against
external pathogens and environmental insults. Although interacting closely and sharing …

The CBM-opathies—a rapidly expanding spectrum of human inborn errors of immunity caused by mutations in the CARD11-BCL10-MALT1 complex

HY Lu, BM Bauman, S Arjunaraja, B Dorjbal… - Frontiers in …, 2018 - frontiersin.org
The caspase recruitment domain family member 11 (CARD11 or CARMA1)—B cell
CLL/lymphoma 10 (BCL10)—MALT1 paracaspase (MALT1)[CBM] signalosome complex …

Hyper-IgE syndrome, 2021 update

Y Minegishi - Allergology International, 2021 - jstage.jst.go.jp
abstract Clinically and pathologically, the patients with hyper-IgE syndrome present similar
skin manifestations to common atopic dermatitis. The original hyper-IgE syndrome is …

Human inborn errors of immunity to herpes viruses

E Jouanguy, V Béziat, TH Mogensen… - Current opinion in …, 2020 - Elsevier
Infections with any of the nine human herpes viruses (HHV) can be asymptomatic or life-
threatening. The study of patients with severe diseases caused by HHVs, in the absence of …