The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Rationale Agonist-based pharmacologic intervention is an accepted approach in treatment
of opioid and tobacco use disorders. Objectives We conducted a systematic review and …

Objective A substantial amount of individuals with substance use disorders (SUD) also meet
criteria for posttraumatic stress disorder (PTSD). Prolonged Exposure (PE) is an effective …

Objective: Contingency management (CM) is often criticized for limited long-term impact.
This meta-analysis focused on objective indices of drug use (ie, urine toxicology) to examine …

This meta-review aimed to summarize the current state of knowledge provided by meta-
analyzes on the efficacy of psychotherapies for substance use disorders. A systematic …

Substance use is a leading cause of disability and death worldwide. Despite the existence of
evidence-based treatments, clinical outcomes are highly variable across individuals, and …

Objective: Previous trials have demonstrated the efficacy and durability of computer-based
cognitive-behavioral therapy (CBT4CBT) as an add-on to standard outpatient care in a …

Background Sustained abstinence is currently the only accepted end‐point for
pharmacotherapy trials for most substance use disorders (SUD), with the exception of …

Abstract Background and Aims Cannabis use is common among people on opioid agonist
treatment (OAT), causing concern for some care providers. However, there is limited and …

Cocaine use disorder is a persistent public health problem for which no widely effective
medications exist. Self-administration procedures, which have shown good predictive …