Radiochemistry for positron emission tomography

J Rong, A Haider, TE Jeppesen, L Josephson… - Nature …, 2023 - nature.com
Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …

Chemistry for Positron Emission Tomography: Recent Advances in 11C‐, 18F‐, 13N‐, and 15O‐Labeling Reactions

X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …

Considerations in the development of reversibly binding PET radioligands for brain imaging

V W. Pike - Current Medicinal Chemistry, 2016 - benthamdirect.com
The development of reversibly binding radioligands for imaging brain proteins in vivo, such
as enzymes, neurotransmitter transporters, receptors and ion channels, with positron …

Selective Conversion of Carbon Dioxide to Formaldehyde via a Bis(silyl)acetal: Incorporation of Isotopically Labeled C1 Moieties Derived from Carbon Dioxide into …

M Rauch, Z Strater, G Parkin - Journal of the American Chemical …, 2019 - ACS Publications
The conversion of carbon dioxide to formaldehyde is a transformation that is of considerable
significance in view of the fact that formaldehyde is a widely used chemical, but this …

New methodologies for the preparation of carbon-11 labeled radiopharmaceuticals

K Dahl, C Halldin, M Schou - Clinical and Translational Imaging, 2017 - Springer
Purpose This short review aims to cover the more recent and promising developments of
carbon-11 (11 C) labeling radiochemistry and its utility in the production of novel …

Carbon-11: radiochemistry and target-based PET molecular imaging applications in oncology, cardiology, and neurology

NS Goud, A Bhattacharya, RK Joshi… - Journal of Medicinal …, 2021 - ACS Publications
The positron emission tomography (PET) molecular imaging technique has gained its
universal value as a remarkable tool for medical diagnosis and biomedical research …

Peptide-based positron emission tomography probes: Current strategies for synthesis and radiolabelling

M Failla, G Floresta, V Abbate - RSC Medicinal Chemistry, 2023 - pubs.rsc.org
In medical imaging, techniques such as magnetic resonance imaging, contrast-enhanced
computerized tomography, and positron emission tomography (PET) are extensively …

11 C [double bond, length as m-dash] O bonds made easily for positron emission tomography radiopharmaceuticals

BH Rotstein, SH Liang, MS Placzek… - Chemical Society …, 2016 - pubs.rsc.org
The positron-emitting radionuclide carbon-11 (11C, t1/2= 20.3 min) possesses the unique
potential for radiolabeling of any biological, naturally occurring, or synthetic organic …

One‐Pot, Direct Incorporation of [11C]CO2 into Carbamates

JM Hooker, AT Reibel, SM Hill… - Angewandte Chemie …, 2009 - Wiley Online Library
Why beat about the bush? An operationally simple and mild reaction based on the direct
fixation of 11CO2 with 1, 8‐diazabicyclo [5.4. 0] undec‐7‐ene (DBU) has been developed …

[HTML][HTML] Cu (I)-catalyzed 11C-carboxylation of boronic acid esters: a rapid and convenient entry to 11C-labeled carboxylic acids, esters and amides

PJ Riss, S Lu, S Telu, FI Aigbirhio… - … Chemie (International ed …, 2012 - ncbi.nlm.nih.gov
Non-invasive imaging with positron emission tomography (PET) allows for quantitative
studies of radiotracer distribution in living subjects and is increasingly used in routine clinical …