Mixed-effects models for the design and analysis of stepped wedge cluster randomized trials: an overview

F Li, JP Hughes, K Hemming… - … Methods in Medical …, 2021 - journals.sagepub.com
The stepped wedge cluster randomized design has received increasing attention in
pragmatic clinical trials and implementation science research. The key feature of the design …

Reporting of stepped wedge cluster randomised trials: extension of the CONSORT 2010 statement with explanation and elaboration

K Hemming, M Taljaard, JE McKenzie, R Hooper… - bmj, 2018 - bmj.com
This report presents the Consolidated Standards of Reporting Trials (CONSORT) extension
for the stepped wedge cluster randomised trial (SW-CRT). The SW-CRT involves …

Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials: A review of trials published 2016–2022

P Nevins, M Ryan, K Davis-Plourde, Y Ouyang… - Clinical …, 2024 - journals.sagepub.com
Background/Aims The stepped-wedge cluster randomized trial (SW-CRT), in which clusters
are randomized to a time at which they will transition to the intervention condition–rather …

Reflection on modern methods: when is a stepped-wedge cluster randomized trial a good study design choice?

K Hemming, M Taljaard - International journal of epidemiology, 2020 - academic.oup.com
The stepped-wedge cluster randomized trial (SW-CRT) involves the sequential transition of
clusters (such as hospitals, public health units or communities) from control to intervention …

Pharmacy practice research–a call to action

V Garcia-Cardenas, CV Rossing… - Research in Social and …, 2020 - Elsevier
Pharmacists have a societal duty of care. How to best provide that type of care requires
scientific study. Pharmacy practice is a scientific discipline that studies the different aspects …

Assessing exposure-time treatment effect heterogeneity in stepped-wedge cluster randomized trials

L Maleyeff, F Li, S Haneuse, R Wang - Biometrics, 2023 - academic.oup.com
A stepped-wedge cluster randomized trial (CRT) is a unidirectional crossover study in which
timings of treatment initiation for clusters are randomized. Because the timing of treatment …

Design and analysis considerations for cohort stepped wedge cluster randomized trials with a decay correlation structure

F Li - Statistics in medicine, 2020 - Wiley Online Library
A stepped wedge cluster randomized trial is a type of longitudinal cluster design that
sequentially switches clusters to intervention over time until all clusters are treated. While the …

Patient safety, cost-effectiveness, and quality of life: reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults—study …

A Sánchez, C Thomas, F Deeken, S Wagner, S Klöppel… - Trials, 2019 - Springer
Background Postoperative delirium is a common disorder in older adults that is associated
with higher morbidity and mortality, prolonged cognitive impairment, development of …

Stepped wedge cluster randomized trials: a methodological overview

F Li, R Wang - World neurosurgery, 2022 - Elsevier
Background Stepped wedge cluster randomized trials enable rigorous evaluations of health
intervention programs in pragmatic settings. In the present study, we aimed to update …

Essential ingredients and innovations in the design and analysis of group-randomized trials

DM Murray, M Taljaard, EL Turner… - Annual Review of …, 2020 - annualreviews.org
This article reviews the essential ingredients and innovations in the design and analysis of
group-randomized trials. The methods literature for these trials has grown steadily since they …