Acute myeloid leukemia (AML) comprises a multifarious and heterogeneous array of
illnesses characterized by the anomalous proliferation of myeloid cells in the bone marrow …

Apoptosis signal-regulated kinase 1 (ASK1) is a member of the mitogen-activated protein
kinase kinase (MAP3K) family, whose activation and regulation are intricately associated …

Hepatocellular carcinoma (HCC) is a highly heterogeneous and malignant cancer with poor
overall survival. The application of sorafenib is a major breakthrough in the treatment of …

Abstract Apolipoprotein C1 (APOC1) is a member of the apolipoprotein family. In recent
years, more and more studies have shown that APOC1 participates in the occurrence and …

Lung cancer is the leading cause of cancer-related mortality worldwide. Non-small cell lung
cancer (NSCLC) is the most common pathological subtype of lung cancer and is associated …

Introduction c-Jun N-terminal kinase (JNK) regulates various biological processes through
the phosphorylation cascade and is closely associated with numerous diseases, including …

The c-Jun N-terminal kinase (JNK) family includes three proteins (JNK1-3) that regulate
many physiological processes, including cell proliferation and differentiation, cell survival …

Abstract C-Jun-N-terminal-kinases (JNKs), members of the mitogen-activated-protein-kinase
family, are significantly linked with neurological and neurodegenerative pathologies and …

The proteasome regulates intracellular processes, maintains biological homeostasis, and
has shown great significance in the study of various diseases, such as neurodegenerative …

Gastric cancer remains a significant health burden globally, especially prevalent in Asian
and European regions. Despite a notable decline in incidence in the United States and …