Metagenomics-enabled microbial surveillance

KKK Ko, KR Chng, N Nagarajan - Nature Microbiology, 2022 - nature.com
Lessons learnt from the COVID-19 pandemic include increased awareness of the potential
for zoonoses and emerging infectious diseases that can adversely affect human health …

Machine learning for microbiologists

F Asnicar, AM Thomas, A Passerini… - Nature Reviews …, 2024 - nature.com
Abstract Machine learning is increasingly important in microbiology where it is used for tasks
such as predicting antibiotic resistance and associating human microbiome features with …

A genomic catalog of Earth's microbiomes

S Nayfach, S Roux, R Seshadri, D Udwary… - Nature …, 2021 - nature.com
The reconstruction of bacterial and archaeal genomes from shotgun metagenomes has
enabled insights into the ecology and evolution of environmental and host-associated …

Microbiome definition re-visited: old concepts and new challenges

G Berg, D Rybakova, D Fischer, T Cernava… - Microbiome, 2020 - Springer
The field of microbiome research has evolved rapidly over the past few decades and has
become a topic of great scientific and public interest. As a result of this rapid growth in …

Improved metagenome binning and assembly using deep variational autoencoders

JN Nissen, J Johansen, RL Allesøe, CK Sønderby… - Nature …, 2021 - nature.com
Despite recent advances in metagenomic binning, reconstruction of microbial species from
metagenomics data remains challenging. Here we develop variational autoencoders for …

Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

JP Shaffer, LF Nothias, LR Thompson, JG Sanders… - Nature …, 2022 - nature.com
Despite advances in sequencing, lack of standardization makes comparisons across studies
challenging and hampers insights into the structure and function of microbial communities …

MetaBAT 2: an adaptive binning algorithm for robust and efficient genome reconstruction from metagenome assemblies

DD Kang, F Li, E Kirton, A Thomas, R Egan, H An… - PeerJ, 2019 - peerj.com
We previously reported on MetaBAT, an automated metagenome binning software tool to
reconstruct single genomes from microbial communities for subsequent analyses of …

Species-level functional profiling of metagenomes and metatranscriptomes

EA Franzosa, LJ McIver, G Rahnavard, LR Thompson… - Nature …, 2018 - nature.com
Functional profiles of microbial communities are typically generated using comprehensive
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …

Current challenges and best-practice protocols for microbiome analysis

R Bharti, DG Grimm - Briefings in bioinformatics, 2021 - academic.oup.com
Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin

NA Bokulich, BD Kaehler, JR Rideout, M Dillon… - Microbiome, 2018 - Springer
Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …