The inexorability of the aging process has sparked the curiosity of human beings since
ancient times. However, despite this interest and the extraordinary scientific advances in the …

Abnormal levels of reactive oxygen species (ROS) and the hypoxic microenvironment within
bone defects are important factors that impede bone repair processes. Herein, an innovative …

Amyotrophic lateral sclerosis (ALS) is a fatal, severely debilitating and rapidly progressing
disorder affecting motor neurons in the brain, brainstem, and spinal cord. Unfortunately …

The RNA-binding protein HuD has been shown to play a crucial role in gene regulation in
the nervous system and is involved in various neurological and psychiatric diseases. In this …

Understanding the mechanisms that drive TDP-43 pathology is integral to combating
amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD) and other …

Many neurological diseases can lead to cognitive impairment in patients, which includes
dementia and mild cognitive impairment and thus create a heavy burden both to their …

Aggregation of TAR-DNA binding protein-43 (TDP-43) is a pathological feature present in
nearly 97% cases of amyotrophic lateral sclerosis (ALS), making it an attractive target for …

RNA binding proteins (RBPs) are increasingly recognized as potential factors influencing
the advancement, prognostication, and immune response in various solid tumors …

Assisted reproduction technology (ART) procedures are often impacted by post-ovulatory
aging (POA), which can lead to reduced fertilization rates and impaired embryo …

Understanding how the assembly of nascent mRNA into a ribonucleoprotein (mRNP)
influences R-loop homeostasis is crucial for gaining insight into the cellular mechanisms that …