Autoimmunity occurs when the immune system recognizes and attacks host tissue. In
addition to genetic factors, environmental triggers (in particular viruses, bacteria and other …

The intracellular protozoan parasite Trypanosoma cruzi is the causative agent of Chagas'
disease, a serious disorder that affects millions of people in Latin America. Despite the …

The vaccine safety surveillance system effectively detected a very rare adverse event,
narcolepsy, in subjects receiving AS03-adjuvanted A (H1N1) pandemic vaccine made using …

Chagas disease is a neglected infectious disease in the tropics and an emerging health
problem in Europe and the USA. In the past decade, a link has been recorded between …

Chagas heart disease (CHD), caused by the protozoan parasite Trypanosoma cruzi, is the
leading cause of infectious myocarditis in the world. The etiology of CHD is unclear and …

Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of individuals infected with the protozoan parasite Trypanosoma cruzi. Since the …

Up to 18 million of individuals are infected by the protozoan parasite Trypanosoma cruzi in
Latin America, one third of whom will develop chronic Chagas disease cardiomyopathy …

Perhaps one of the most intriguing aspects of human Chagas disease is the complex
network of events that underlie the generation of protective versus pathogenic immune …

The extent of inflammation, fibrosis, and progression of chronic Chagas heart disease
(cChHD) was associated with persistence of parasite DNA in cardiac lesions of necropsies …

No randomized clinical trials regarding the etiological treatment of chronic Chagas disease
can be found in the medical literature. However, other 'evidence'sustaining the use of anti …