[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology
In global terms, respiratory viral infection is a major cause of morbidity and mortality. Infancy,
in particular, is a time of increased disease susceptibility and severity. Early-life viral …
in particular, is a time of increased disease susceptibility and severity. Early-life viral …
Respiratory syncytial virus—a comprehensive review
AT Borchers, C Chang, ME Gershwin… - Clinical reviews in allergy …, 2013 - Springer
Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …
childhood and is associated with significant morbidity and mortality. Although there have …
The airway epithelium: soldier in the fight against respiratory viruses
M Vareille, E Kieninger, MR Edwards… - Clinical microbiology …, 2011 - Am Soc Microbiol
The airway epithelium acts as a frontline defense against respiratory viruses, not only as a
physical barrier and through the mucociliary apparatus but also through its immunological …
physical barrier and through the mucociliary apparatus but also through its immunological …
The human immune response to respiratory syncytial virus infection
CD Russell, SA Unger, M Walton… - Clinical microbiology …, 2017 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is an important etiological agent of respiratory infections,
particularly in children. Much information regarding the immune response to RSV comes …
particularly in children. Much information regarding the immune response to RSV comes …
Viral and host factors in human respiratory syncytial virus pathogenesis
Human respiratory syncytial virus (RSV) was first isolated in 1956 from a laboratory
chimpanzee with upper respiratory tract disease (for general reviews, see references 21, 57 …
chimpanzee with upper respiratory tract disease (for general reviews, see references 21, 57 …
Bronchiolitis
RL Smyth, PJM Openshaw - The lancet, 2006 - thelancet.com
Bronchiolitis is a distressing, potentially life-threatening respiratory condition that affects
young babies. Around 2–3% of all infants younger than 1 year are admitted to hospital with …
young babies. Around 2–3% of all infants younger than 1 year are admitted to hospital with …
MERS-CoV infection is associated with downregulation of genes encoding Th1 and Th2 cytokines/chemokines and elevated inflammatory innate immune response in …
MERS-CoV, a highly pathogenic virus in humans, is associated with high morbidity and case
fatality. Inflammatory responses have a significant impact on MERS-CoV pathogenesis and …
fatality. Inflammatory responses have a significant impact on MERS-CoV pathogenesis and …
Alveolar macrophage–derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes
M Goritzka, S Makris, F Kausar, LR Durant… - Journal of Experimental …, 2015 - rupress.org
Type I interferons (IFNs) are important for host defense from viral infections, acting to restrict
viral production in infected cells and to promote antiviral immune responses. However, the …
viral production in infected cells and to promote antiviral immune responses. However, the …
Neutrophil extracellular traps cause airway obstruction during respiratory syncytial virus disease
B Cortjens, OJ De Boer, R De Jong… - The Journal of …, 2016 - Wiley Online Library
Human respiratory syncytial virus (RSV) is the most important cause of severe lower
respiratory tract disease (LRTD) in young children worldwide. Extensive neutrophil …
respiratory tract disease (LRTD) in young children worldwide. Extensive neutrophil …