Engineering peptide drug therapeutics through chemical conjugation and implication in clinics

SFA Rizvi, H Zhang, Q Fang - Medicinal Research Reviews, 2024 - Wiley Online Library
The development of peptide drugs has made tremendous progress in the past few decades
because of the advancements in modification chemistry and analytical technologies. The …

Peptide-drug conjugates: design, chemistry, and drug delivery system as a novel cancer theranostic

SFA Rizvi, L Zhang, H Zhang… - ACS Pharmacology & …, 2024 - ACS Publications
The emergence of peptide–drug conjugates (PDCs) that utilize target-oriented peptide
moieties as carriers of cytotoxic payloads, interconnected with various cleavable …

Iron oxide nanoparticles: The versatility of the magnetic and functionalized nanomaterials in targeting drugs, and gene deliveries with effectual magnetofection

S Albukhaty, GM Sulaiman, H Al-Karagoly… - Journal of Drug Delivery …, 2024 - Elsevier
Iron oxide nanoparticles have been extensively used for different biomedical purposes,
especially for targeted drug delivery, and gene transfers, owing to their unique features, ie …

Mechanisms of myocardial toxicity of antitumor drugs and potential therapeutic strategies: A review of the literature

Y Jia, Q Wu, Z Yang, R Sun, K Zhang, X Guo… - Current Problems in …, 2024 - Elsevier
With the successive development of chemotherapy drugs, good results have been achieved
in clinical application. However, myocardial toxicity is the biggest challenge. Anthracyclines …

Magnetic Relaxation Switching Assay Using IFNα-2b-Conjugated Superparamagnetic Nanoparticles for Anti-Interferon Antibody Detection

B Nikolaev, L Yakovleva, V Fedorov, N Yudintceva… - Biosensors, 2023 - mdpi.com
Type I interferons, particularly IFNα-2b, play essential roles in eliciting adaptive and innate
immune responses, being implicated in the pathogenesis of various diseases, including …

[HTML][HTML] ADME-tox prediction and molecular docking studies of two lead flavonoids from the roots of Tephrosia egregia sandw and the gastroprotective effects of its …

MEF Rogério, HV Chaves, IR Pinto… - BIO …, 2022 - ingentaconnect.com
Background: This study aimed to predict the pharmacokinetic and toxicological properties of
lead flavonoids from the roots of T. egregia [praecansone A (1) and pongachalcone (2)], and …

Renal Effects of Graphite Oxide Sheets in Albino Rats ( Rattus norvegicus): A Preliminary Study

AN Muhammad, A Ijaz, A Khalid, K Rafique… - BIO …, 2024 - scienceopen.com
Although diamond-like carbon-coated joint replacements are widely recommended for full
bone replacements in humans, their clinical application is substantially limited by …

Multifunctional Magnetic Nanoparticles in Electrochemical Sensors for Pharmaceuticals

G Aylaz, Y Bozkurt, B Tüzün… - … Magnetic Nanoparticles in …, 2025 - taylorfrancis.com
Electrochemical sensors are used in the pharmaceutical industry for their sensitivity, high-
accuracy, quick response times, low detection limits, user-friendliness, and reasonably …