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Engineering peptide drug therapeutics through chemical conjugation and implication in clinics
SFA Rizvi, H Zhang, Q Fang - Medicinal Research Reviews, 2024 - Wiley Online Library
The development of peptide drugs has made tremendous progress in the past few decades
because of the advancements in modification chemistry and analytical technologies. The …
because of the advancements in modification chemistry and analytical technologies. The …
Peptide-drug conjugates: design, chemistry, and drug delivery system as a novel cancer theranostic
SFA Rizvi, L Zhang, H Zhang… - ACS Pharmacology & …, 2024 - ACS Publications
The emergence of peptide–drug conjugates (PDCs) that utilize target-oriented peptide
moieties as carriers of cytotoxic payloads, interconnected with various cleavable …
moieties as carriers of cytotoxic payloads, interconnected with various cleavable …
Iron oxide nanoparticles: The versatility of the magnetic and functionalized nanomaterials in targeting drugs, and gene deliveries with effectual magnetofection
Iron oxide nanoparticles have been extensively used for different biomedical purposes,
especially for targeted drug delivery, and gene transfers, owing to their unique features, ie …
especially for targeted drug delivery, and gene transfers, owing to their unique features, ie …
Mechanisms of myocardial toxicity of antitumor drugs and potential therapeutic strategies: A review of the literature
Y Jia, Q Wu, Z Yang, R Sun, K Zhang, X Guo… - Current Problems in …, 2024 - Elsevier
With the successive development of chemotherapy drugs, good results have been achieved
in clinical application. However, myocardial toxicity is the biggest challenge. Anthracyclines …
in clinical application. However, myocardial toxicity is the biggest challenge. Anthracyclines …
Magnetic Relaxation Switching Assay Using IFNα-2b-Conjugated Superparamagnetic Nanoparticles for Anti-Interferon Antibody Detection
B Nikolaev, L Yakovleva, V Fedorov, N Yudintceva… - Biosensors, 2023 - mdpi.com
Type I interferons, particularly IFNα-2b, play essential roles in eliciting adaptive and innate
immune responses, being implicated in the pathogenesis of various diseases, including …
immune responses, being implicated in the pathogenesis of various diseases, including …
[HTML][HTML] ADME-tox prediction and molecular docking studies of two lead flavonoids from the roots of Tephrosia egregia sandw and the gastroprotective effects of its …
MEF Rogério, HV Chaves, IR Pinto… - BIO …, 2022 - ingentaconnect.com
Background: This study aimed to predict the pharmacokinetic and toxicological properties of
lead flavonoids from the roots of T. egregia [praecansone A (1) and pongachalcone (2)], and …
lead flavonoids from the roots of T. egregia [praecansone A (1) and pongachalcone (2)], and …
Renal Effects of Graphite Oxide Sheets in Albino Rats ( Rattus norvegicus): A Preliminary Study
AN Muhammad, A Ijaz, A Khalid, K Rafique… - BIO …, 2024 - scienceopen.com
Although diamond-like carbon-coated joint replacements are widely recommended for full
bone replacements in humans, their clinical application is substantially limited by …
bone replacements in humans, their clinical application is substantially limited by …
Multifunctional Magnetic Nanoparticles in Electrochemical Sensors for Pharmaceuticals
Electrochemical sensors are used in the pharmaceutical industry for their sensitivity, high-
accuracy, quick response times, low detection limits, user-friendliness, and reasonably …
accuracy, quick response times, low detection limits, user-friendliness, and reasonably …