Recent advances of imidazole-containing derivatives as anti-tubercular agents

YL Fan, XH **, ZP Huang, HF Yu, ZG Zeng… - European journal of …, 2018 - Elsevier
Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …

Nitro-group-containing drugs

K Nepali, HY Lee, JP Liou - Journal of medicinal chemistry, 2018 - ACS Publications
The nitro group is considered to be a versatile and unique functional group in medicinal
chemistry. Despite a long history of use in therapeutics, the nitro group has toxicity issues …

Multidirectional efficacy of biologically active nitro compounds included in medicines

D Olender, J Żwawiak, L Zaprutko - Pharmaceuticals, 2018 - mdpi.com
The current concept in searching for new bioactive products, including mainly original active
substances with potential application in pharmacy and medicine, is based on compounds …

[BOOK][B] Microwave heating as a tool for sustainable chemistry

NE Leadbeater - 2010 - taylorfrancis.com
Shorter reaction times, higher product yields, and enhanced selectivity are some of the
advantages microwave heating has over conventional methods, causing its use to transition …

Nitroaromatic antibiotics as nitrogen oxide sources

AM Rice, Y Long, SB King - Biomolecules, 2021 - mdpi.com
Nitroaromatic antibiotics show activity against anaerobic bacteria and parasites, finding use
in the treatment of Heliobacter pylori infections, tuberculosis, trichomoniasis, human African …

Antituberculosis drug research: a critical overview

Beena, DS Rawat - Medicinal research reviews, 2013 - Wiley Online Library
The increasing drug resistance of M ycobacterium tuberculosis to the currently used drugs
and HIV coinfection has caused alarm in the international scientific community …

Nitroimidazoles for the treatment of TB: past, present and future

T Mukherjee, H Boshoff - Future medicinal chemistry, 2011 - Taylor & Francis
Tuberculosis remains a leading cause of death resulting from an infectious agent, and the
spread of multi-and extensively drug-resistant strains of Mycobacterium tuberculosis poses a …

Ruthenium (II) Polypyridyl Complexes and Metronidazole Derivatives: A Powerful Combination in the Design of Photoresponsive Antibacterial Agents Effective under …

GE Giacomazzo, L Conti, C Fagorzi, M Pagliai… - Inorganic …, 2023 - ACS Publications
Ruthenium (II) polypyridyl complexes (RPCs) are gaining momentum in photoactivated
chemotherapy (PACT), thanks to the possibility of overcoming the classical reliance on …

Unpacking the Pathogen Box—an open source tool for fighting neglected tropical disease

CGL Veale - ChemMedChem, 2019 - Wiley Online Library
Abstract The Pathogen Box is a 400‐strong collection of drug‐like compounds, selected for
their potential against several of the world's most important neglected tropical diseases …

[3+ 2] Cycloaddition of diaryldiazomethanes with (E)-3, 3, 3-trichloro-1-nitroprop-1-ene: An experimental, theoretical and structural study

K Kula, J Dobosz, R Jasiński, A Kącka-Zych… - Journal of Molecular …, 2020 - Elsevier
The participation of different diaryldiazomethanes as three-atom components (TACs) in [3+
2] cycloaddition reactions with (E)-3, 3, 3-trichloro-1-nitroprop-1-ene was analysed. All of the …