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[HTML][HTML] MicroRNAs: synthesis, mechanism, function, and recent clinical trials
MicroRNAs (miRNAs) are a class of small, endogenous RNAs of 21–25 nucleotides (nts) in
length. They play an important regulatory role in animals and plants by targeting specific …
length. They play an important regulatory role in animals and plants by targeting specific …
RNA silencing as a plant immune system against viruses
O Voinnet - TRENDS in Genetics, 2001 - cell.com
Abstract 'RNA silencing'refers to related processes of post-trancriptional control of gene
expression found in plants, animals and fungi. A unifying feature of RNA silencing is that it …
expression found in plants, animals and fungi. A unifying feature of RNA silencing is that it …
A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA
The 21-nucleotide small temporal RNA (stRNA) let-7 regulates developmental timing in
Caenorhabditis elegans and probably in other bilateral animals. We present in vivo and in …
Caenorhabditis elegans and probably in other bilateral animals. We present in vivo and in …
MicroRNAs in plants
BJ Reinhart, EG Weinstein, MW Rhoades… - Genes & …, 2002 - genesdev.cshlp.org
MicroRNAs (miRNAs) are an extensive class of∼ 22-nucleotide noncoding RNAs thought to
regulate gene expression in metazoans. We find that miRNAs are also present in plants …
regulate gene expression in metazoans. We find that miRNAs are also present in plants …
Prediction of plant microRNA targets
We predict regulatory targets for 14 Arabidopsis microRNAs (miRNAs) by identifying mRNAs
with near complementarity. Complementary sites within predicted targets are conserved in …
with near complementarity. Complementary sites within predicted targets are conserved in …
[HTML][HTML] Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
SM Elbashir, J Martinez, A Patkaniowska… - The EMBO …, 2001 - embopress.org
Duplexes of 21–23 nucleotide (nt) RNAs are the sequence‐specific mediators of RNA
interference (RNAi) and post‐transcriptional gene silencing (PTGS). Synthetic, short …
interference (RNAi) and post‐transcriptional gene silencing (PTGS). Synthetic, short …
CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana
Background: In metazoans, microRNAs, or miRNAs, constitute a growing family of small
regulatory RNAs that are usually 19–25 nucleotides in length. They are processed from …
regulatory RNAs that are usually 19–25 nucleotides in length. They are processed from …
Temporal regulation of shoot development in Arabidopsis thalianaby miR156 and its target SPL3
G Wu, RS Poethig - 2006 - journals.biologists.com
SPL3, SPL4 and SPL5 (SPL3/4/5) are closely related members of the SQUAMOSA
PROMOTER BINDING PROTEIN-LIKE family of transcription factors in Arabidopsis, and …
PROMOTER BINDING PROTEIN-LIKE family of transcription factors in Arabidopsis, and …
P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA function
The molecular basis for virus-induced disease in plants has been a long-standing mystery.
Infection of Arabidopsis by Turnip mosaic virus (TuMV) induces a number of developmental …
Infection of Arabidopsis by Turnip mosaic virus (TuMV) induces a number of developmental …
[HTML][HTML] MicroRNA biogenesis and function in plants
X Chen - FEBS letters, 2005 - Elsevier
A microRNA (miRNA) is a 21–24 nucleotide RNA product of a non-protein-coding gene.
Plants, like animals, have a large number of miRNA-encoding genes in their genomes. The …
Plants, like animals, have a large number of miRNA-encoding genes in their genomes. The …