Recent advances on cell culture platforms for in vitro drug screening and cell therapies: from conventional to microfluidic strategies

BD Cardoso, EMS Castanheira… - Advanced …, 2023 - Wiley Online Library
The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …

Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021 - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

[HTML][HTML] Development of glass-based microfluidic devices: A review on its fabrication and biologic applications

S Aralekallu, R Boddula, V Singh - Materials & Design, 2023 - Elsevier
The advent of glass-based microfluidic devices further revolutionized in microfluidic
technology due to the several advantageous properties in terms of photonics, electronics …

Glucose detection devices and methods based on metal–organic frameworks and related materials

M Adeel, K Asif, MM Rahman, S Daniele… - Advanced Functional …, 2021 - Wiley Online Library
Assessment of glucose concentration is important in the diagnosis and treatment of
diabetes. Since the introduction of enzymatic glucose biosensors, scientific and …

Carbon fiber doped thermosetting elastomer for flexible sensors: physical properties and microfabrication

A Khosla, S Shah, MDNI Shiblee, SH Mir… - Scientific reports, 2018 - nature.com
We have developed conductive microstructures using micropatternable and conductive
hybrid nanocomposite polymer. In this method carbon fibers (CFs) were blended into …

Small but perfectly formed? Successes, challenges, and opportunities for microfluidics in the chemical and biological sciences

DT Chiu, AJ Demello, D Di Carlo, PS Doyle, C Hansen… - Chem, 2017 - cell.com
Microfluidic systems are pervasive in many areas of experimental science, but what are the
real advantages of this technology? We describe some of the features and properties that …

The past, present and potential for microfluidic reactor technology in chemical synthesis

KS Elvira, XC i Solvas, RCR Wootton, AJ Demello - Nature chemistry, 2013 - nature.com
The past two decades have seen far-reaching progress in the development of microfluidic
systems for use in the chemical and biological sciences. Here we assess the utility of …

Why microfluidics? Merits and trends in chemical synthesis

Y Liu, X Jiang - Lab on a Chip, 2017 - pubs.rsc.org
The intrinsic limitations of conventional batch synthesis have hindered its applications in
both solving classical problems and exploiting new frontiers. Microfluidic technology offers a …

Deciding whether to go with the flow: evaluating the merits of flow reactors for synthesis

RL Hartman, JP McMullen… - Angewandte Chemie …, 2011 - Wiley Online Library
The fine chemicals and pharmaceutical industries are transforming how their products are
manufactured, where economically favorable, from traditional batchwise processes to …

Novel process windows for enabling, accelerating, and uplifting flow chemistry

V Hessel, D Kralisch, N Kockmann, T Noël… - …, 2013 - Wiley Online Library
Abstract Novel Process Windows make use of process conditions that are far from
conventional practices. This involves the use of high temperatures, high pressures, high …