The global public health significance of Plasmodium vivax

KE Battle, PW Gething, IRF Elyazar, CL Moyes… - Advances in …, 2012 - Elsevier
Plasmodium vivax occurs globally and thrives in both temperate and tropical climates. Here,
we review the evidence of the biological limits of its contemporary distribution and the global …

Antimicrobial peptides: a new class of antimalarial drugs?

N Vale, L Aguiar, P Gomes - Frontiers in Pharmacology, 2014 - frontiersin.org
A range of antimicrobial peptides (AMP) exhibit activity on malaria parasites, Plasmodium
spp., in their blood or mosquito stages, or both. These peptides include a diverse array of …

The Plasmodium bottleneck: malaria parasite losses in the mosquito vector

RC Smith, J Vega-Rodríguez… - Memórias do Instituto …, 2014 - SciELO Brasil
Nearly one million people are killed every year by the malaria parasite Plasmodium.
Although the disease-causing forms of the parasite exist only in the human blood …

Trypanosoma cruzi Immune Response Modulation Decreases Microbiota in Rhodnius prolixus Gut and Is Crucial for Parasite Survival and Development

DP Castro, CS Moraes, MS Gonzalez, NA Ratcliffe… - PLoS …, 2012 - journals.plos.org
Trypanosoma cruzi in order to complete its development in the digestive tract of Rhodnius
prolixus needs to overcome the immune reactions and microbiota trypanolytic activity of the …

Mosquito gut antiparasitic and antiviral immunity

RG Saraiva, S Kang, ML Simoes… - Developmental & …, 2016 - Elsevier
Mosquitoes are responsible for the transmission of diseases with a serious impact on global
human health, such as malaria and dengue. All mosquito-transmitted pathogens complete …

Anopheles metabolic proteins in malaria transmission, prevention and control: a review

EO Adedeji, OO Ogunlana, S Fatumo, T Beder… - Parasites & vectors, 2020 - Springer
The increasing resistance to currently available insecticides in the malaria vector,
Anopheles mosquitoes, hampers their use as an effective vector control strategy for the …

Hemocyte differentiation mediates the mosquito late-phase immune response against Plasmodium in Anopheles gambiae

RC Smith, C Barillas-Mury… - Proceedings of the …, 2015 - pnas.org
Plasmodium parasites must complete development in the mosquito vector for transmission
to occur. The mosquito innate immune response is remarkably efficient in limiting parasite …

Rhodnius prolixus: from physiology by Wigglesworth to recent studies of immune system modulation by Trypanosoma cruzi and Trypanosoma rangeli

P Azambuja, ES Garcia, PJ Waniek, CS Vieira… - Journal of insect …, 2017 - Elsevier
This review is dedicated to the memory of Professor Sir Vincent B. Wigglesworth (VW) in
recognition of his many pioneering contributions to insect physiology which, even today …

Ambient temperature and dietary supplementation interact to shape mosquito vector competence for malaria

CC Murdock, S Blanford, S Luckhart… - Journal of insect …, 2014 - Elsevier
The extent to which environmental factors influence the ability of Anopheles mosquitoes to
transmit malaria parasites remains poorly explored. Environmental variation, such as …

Antiparasitic peptides

J Pretzel, F Mohring, S Rahlfs, K Becker - Yellow Biotechnology I: Insect …, 2013 - Springer
<? xm-replace_text {Heading}?> Abstract The most important parasitic diseases, malaria,
leishmaniasis, trypanosomiasis, and schistosomiasis, are a great burden to mankind …