Inflammatory reactions could be both beneficial and detrimental to the brain, depending on
strengths of their activation in various stages of neurodegeneration. Mild activation of …

In recent years, natural products, which originate from plants, animals, and fungi, together
with their bioactive compounds have been intensively explored and studied for their …

Alzheimer's disease (AD) is associated with severe cognitive impairments as well as some
metabolic defects. Scant studies in animal models indicate a link between probiotics and …

Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …

Background: Probiotics and their nutrient sources (prebiotics) have been shown to have
positive effects on different organs of the host. The idea of their potential benefits on Central …

Alzheimer's disease (AD) is a gradually debilitating disease that leads to dementia. The
molecular mechanisms underlying AD are still not clear, and at present no reliable …

The gut‐brain axis is increasingly recognized as an important pathway of communication
and of physiological regulation, and gut microbiota seems to play a significant role in this …

Abstract Silence information regulator 1 (SIRT1), a member of the sirtuin family, targets
histones and many non-histone proteins and participates in various physiological functions …

Abstract Coronavirus disease 2019 (COVID-19), which resulted from the pandemic outbreak
of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes a massive …

Reactive oxygen species are generated as a by-product of routine biochemical reactions.
However, dysfunction of the antioxidant system or mutations in gene function may result in …