The rise of regulatory RNA
Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …
suggests that RNA is not only functional as a messenger between DNA and protein but also …
Cancer stem cells and chemoresistance: The smartest survives the raid
J Zhao - Pharmacology & therapeutics, 2016 - Elsevier
Chemoresistant metastatic relapse of minimal residual disease plays a significant role for
poor prognosis of cancer. Growing evidence supports a critical role of cancer stem cell …
poor prognosis of cancer. Growing evidence supports a critical role of cancer stem cell …
The oncogenic role of miR-155 in breast cancer
Abstract miR-155 is an oncogenic miRNA with well described roles in leukemia. However,
additional roles of miR-155 in breast cancer progression have recently been described. A …
additional roles of miR-155 in breast cancer progression have recently been described. A …
MicroRNAs: novel regulators in the hallmarks of human cancer
K Ruan, X Fang, G Ouyang - Cancer letters, 2009 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs of 18–25 nucleotides in length that
function as negative regulators. miRNAs post-transcriptionally regulate gene expression by …
function as negative regulators. miRNAs post-transcriptionally regulate gene expression by …
A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion
HG Møller, AP Rasmussen, HH Andersen… - Molecular …, 2013 - Springer
Glioblastoma multiforme (GBM) is an incurable form of brain cancer with a very poor
prognosis. Because of its highly invasive nature, it is impossible to remove all tumor cells …
prognosis. Because of its highly invasive nature, it is impossible to remove all tumor cells …
Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance
Z Wang, Y Li, A Ahmad, AS Azmi, D Kong… - Drug resistance …, 2010 - Elsevier
Although chemotherapy is an important therapeutic strategy for cancer treatment, it fails to
eliminate all tumor cells due to intrinsic or acquired drug resistance, which is the most …
eliminate all tumor cells due to intrinsic or acquired drug resistance, which is the most …
miRNA control of tumor cell invasion and metastasis
MicroRNAs have emerged as a novel class of noncoding RNAs that regulate gene
expression at the post‐translational level in almost every biological event. A large body of …
expression at the post‐translational level in almost every biological event. A large body of …
Pathogenesis of human adenomyosis: current understanding and its association with infertility
KN Khan, A Fujishita, T Mori - Journal of clinical medicine, 2022 - mdpi.com
The aim of this review article was to summarize our current understanding on the etiologies
and pathogenesis of human adenomyosis and to clarify the relative association between …
and pathogenesis of human adenomyosis and to clarify the relative association between …
miR-200 enhances mouse breast cancer cell colonization to form distant metastases
Background The development of metastases involves the dissociation of cells from the
primary tumor to penetrate the basement membrane, invade and then exit the vasculature to …
primary tumor to penetrate the basement membrane, invade and then exit the vasculature to …
The role of microRNAs in endometriosis and associated reproductive conditions
EMC Ohlsson Teague, CG Print… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND microRNAs (miRNAs) are short, single-stranded RNAs that regulate gene
expression at the post-transcriptional level. Recent research has shown that miRNAs and …
expression at the post-transcriptional level. Recent research has shown that miRNAs and …