The biological effects of cannabinoids, the major constituents of the ancient medicinal plant
Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled …

Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …

Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

The outcomes of the Canakinumab Anti-inflammatory Thrombosis Outcome Study
(CANTOS) trial have unequivocally proven that inflammation is a key driver of …

The discovery of the endocannabinoid system, comprising the G‐protein coupled
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …

The growing popularity of medical and recreational consumption of cannabis, especially
among the youth, raises immediate concerns regarding its safety and long-terms effects. The …

The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …

Marijuana is the most widely used illicit drug, with approximately 200 million users
worldwide. Once illegal throughout the United States, cannabis is now legal for medicinal …

The endocannabinoid system (ECS), comprising two G protein-coupled receptors (the
cannabinoid receptors 1 and 2 [CB1 and CB2] for marijuana's psychoactive principle∆ 9 …