The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

FJI Fowkes, JS Richards, JA Simpson… - PLoS medicine, 2010 - journals.plos.org
Background One of the criteria to objectively prioritize merozoite antigens for malaria
vaccine development is the demonstration that naturally acquired antibodies are associated …

Artemisinin resistance and malaria elimination: Where are we now?

B Hanboonkunupakarn, J Tarning… - Frontiers in …, 2022 - frontiersin.org
The emergence of artemisinin resistance is a major obstacle to the global malaria
eradication/elimination programs. Artemisinin is a very fast-acting antimalarial drug and is …

A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray

PD Crompton, MA Kayala, B Traore… - Proceedings of the …, 2010 - National Acad Sciences
Abs are central to malaria immunity, which is only acquired after years of exposure to
Plasmodium falciparum (Pf). Despite the enormous worldwide burden of malaria, the targets …

Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine

KA Collins, R Snaith, MG Cottingham, SC Gilbert… - Scientific reports, 2017 - nature.com
The leading malaria vaccine in development is the circumsporozoite protein (CSP)-based
particle vaccine, RTS, S, which targets the pre-erythrocytic stage of Plasmodium falciparum …

Breadth and Magnitude of Antibody Responses to Multiple Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Clinical Malaria

FHA Osier, G Fegan, SD Polley, L Murungi… - Infection and …, 2008 - Am Soc Microbiol
Individuals living in areas where malaria is endemic are repeatedly exposed to many
different malaria parasite antigens. Studies on naturally acquired antibody-mediated …

Immunoglobulin G Subclass-Specific Responses against Plasmodium falciparum Merozoite Antigens Are Associated with Control of Parasitemia and Protection from …

DI Stanisic, JS Richards, FJ McCallum… - Infection and …, 2009 - Am Soc Microbiol
Substantial evidence indicates that antibodies to Plasmodium falciparum merozoite antigens
play a role in protection from malaria, although the precise targets and mechanisms …

New antigens for a multicomponent blood-stage malaria vaccine

FH Osier, MJ Mackinnon, C Crosnier, G Fegan… - Science translational …, 2014 - science.org
An effective blood-stage vaccine against Plasmodium falciparum remains a research
priority, but the number of antigens that have been translated into multicomponent vaccines …

The Relationship between RTS,S Vaccine-Induced Antibodies, CD4+ T Cell Responses and Protection against Plasmodium falciparum Infection

MT White, P Bejon, A Olotu, JT Griffin, EM Riley… - PloS one, 2013 - journals.plos.org
Vaccination with the pre-erythrocytic malaria vaccine RTS, S induces high levels of
antibodies and CD4+ T cells specific for the circumsporozoite protein (CSP). Using a …

Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and …

DI Stanisic, FJI Fowkes, M Koinari, S Javati… - Infection and …, 2015 - Am Soc Microbiol
Individuals in areas of Plasmodium falciparum endemicity develop immunity to malaria after
repeated exposure. Knowledge of the acquisition and nature of protective immune …

Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants

SR Bonam, L Rénia, G Tadepalli, J Bayry, HMS Kumar - Vaccines, 2021 - mdpi.com
Malaria—a parasite vector-borne disease—is a global health problem, and Plasmodium
falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in …