Microtubule nucleation is regulated by the γ-tubulin ring complex (γTuRC) and related γ-
tubulin complexes, providing spatial and temporal control over the initiation of microtubule …

The number, length, distribution and polarity of microtubules are largely controlled by
microtubule-organizing centres, which nucleate and anchor microtubule minus ends in a …

The highly conserved protein γ-tubulin is required for microtubule nucleation in vivo. When
viewed in the electron microscope, a highly purified γtubulin complex from Xenopus …

Mammalian polo-like kinase 1 (Plk1) is structurally related to the polo gene product of
Drosophila melanogaster, Cdc5p of Saccharomyces cerevisiae, and plo1+ of …

Microtubules are born and reborn continuously, even during quiescence. These polymers
are nucleated from templates, namely γ-tubulin ring complexes (γ-TuRCs) and severed …

Aspergillus nidulans is an important experimental organism, and it is a model organism for
the genus Aspergillus that includes serious pathogens as well as commercially important …

Antlsem from scleroderma patients that react widely with centrosomes in plants and animals
were used to isolate cDNA8 encoding a novel centrosomal proteln. The nucleotlde …

The centrosome plays a major role in the spatial organization of the microtubular network
and has a controlled cycle of duplication, the two duplicated centrosomes functioning as …

The centrosome plays an important role in maintenance of cell polarity and in progression
through the cell cycle by determining the number, polarity, and organization of interphase …

We have cloned and characterized y-tubulin genes from both X. laevis and S. pombe, and
partial genes from maize, diatom, and a budding yeast. The proteins encoded by these …