Unravelling cell migration: defining movement from the cell surface

F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …

Physics of liquid crystals in cell biology

A Doostmohammadi, B Ladoux - Trends in cell biology, 2022 - cell.com
The past decade has witnessed a rapid growth in understanding of the pivotal roles of
mechanical stresses and physical forces in cell biology. As a result, an integrated view of …

Liquid crystal–based open surface microfluidics manipulate liquid mobility and chemical composition on demand

Y Xu, AM Rather, Y Yao, JC Fang, RS Mamtani… - Science …, 2021 - science.org
The ability to control both the mobility and chemical compositions of microliter-scale
aqueous droplets is an essential prerequisite for next-generation open surface microfluidics …

Morphogens enable interacting supracellular phases that generate organ architecture

S Yang, KH Palmquist, L Nathan, CR Pfeifer… - Science, 2023 - science.org
During vertebrate organogenesis, increases in morphological complexity are tightly coupled
to morphogen expression. In this work, we studied how morphogens influence self …

Symmetry, thermodynamics, and topology in active matter

MJ Bowick, N Fakhri, MC Marchetti, S Ramaswamy - Physical Review X, 2022 - APS
The name active matter refers to any collection of entities that individually use free energy to
generate their own motion and forces. Through interactions, active particles spontaneously …

Active nematics across scales from cytoskeleton organization to tissue morphogenesis

L Balasubramaniam, RM Mège, B Ladoux - Current Opinion in Genetics & …, 2022 - Elsevier
Biological tissues are composed of various cell types working cooperatively to perform their
respective function within organs and the whole body. During development, embryogenesis …

Epithelia are multiscale active liquid crystals

JM Armengol-Collado, LN Carenza, J Eckert… - Nature Physics, 2023 - nature.com
Biological processes such as embryogenesis, wound healing and cancer progression rely
on the ability of epithelial cells to coordinate their mechanical activity over length scales that …

Mechanical stress driven by rigidity sensing governs epithelial stability

S Sonam, L Balasubramaniam, SZ Lin, YMY Ivan… - Nature physics, 2023 - nature.com
Epithelia act as barriers against environmental stresses. They are continuously exposed to
various mechanical stress and abrasion, which impact epithelial integrity. The impact of the …

Topological defect-mediated morphodynamics of active–active interfaces

DQ Zhang, PC Chen, ZY Li… - Proceedings of the …, 2022 - National Acad Sciences
Physical interfaces widely exist in nature and engineering. Although the formation of passive
interfaces is well elucidated, the physical principles governing active interfaces remain …

Confined cell migration along extracellular matrix space in vivo

O Chepizhko, JM Armengol-Collado… - Proceedings of the …, 2025 - pnas.org
Collective migration of cancer cells is often interpreted using concepts derived from the
physics of active matter, but the experimental evidence is mostly restricted to observations …