Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

[HTML][HTML] Current strategies for brain drug delivery

X Dong - Theranostics, 2018 - ncbi.nlm.nih.gov
The blood-brain barrier (BBB) has been a great hurdle for brain drug delivery. The BBB in
healthy brain is a diffusion barrier essential for protecting normal brain function by impeding …

5-aminolevulinic acid photodynamic therapy for the treatment of high-grade gliomas

K Mahmoudi, KL Garvey, A Bouras, G Cramer… - Journal of neuro …, 2019 - Springer
Introduction Photodynamic therapy (PDT) is a two-step treatment involving the
administration of a photosensitive agent followed by its activation at a specific light …

A detailed insight of the tumor targeting using nanocarrier drug delivery system

S Batool, S Sohail, F ud Din, AH Alamri… - Drug Delivery, 2023 - Taylor & Francis
Human struggle against the deadly disease conditions is continued since ages. The
contribution of science and technology in fighting against these diseases cannot be ignored …

Recent trends of the bio-inspired nanoparticles in cancer theranostics

VS Madamsetty, A Mukherjee… - Frontiers in …, 2019 - frontiersin.org
In recent years, various nanomaterials have emerged as an exciting tool in cancer
theranostic applications due to their multifunctional property and intrinsic molecular property …

Blood-brain barrier, blood-brain tumor barrier, and fluorescence-guided neurosurgical oncology: delivering optical labels to brain tumors

E Belykh, KV Shaffer, C Lin, VA Byvaltsev… - Frontiers in …, 2020 - frontiersin.org
Recent advances in maximum safe glioma resection have included the introduction of a host
of visualization techniques to complement intraoperative white-light imaging of tumors …

Current trends in cancer nanotheranostics: metallic, polymeric, and lipid-based systems

CO Silva, JO Pinho, JM Lopes, AJ Almeida, MM Gaspar… - Pharmaceutics, 2019 - mdpi.com
Theranostics has emerged in recent years to provide an efficient and safer alternative in
cancer management. This review presents an updated description of nanotheranostic …

[HTML][HTML] Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases

MI Teixeira, CM Lopes, MH Amaral, PC Costa - Colloids and Surfaces B …, 2023 - Elsevier
The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain,
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …

Intranasal delivery of nanoformulations: a potential way of treatment for neurological disorders

SU Islam, A Shehzad, MB Ahmed, YS Lee - Molecules, 2020 - mdpi.com
Although the global prevalence of neurological disorders such as Parkinson's disease,
Alzheimer's disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing …

Lymph-targeted high-density lipoprotein-mimetic nanovaccine for multi-antigenic personalized cancer immunotherapy

M Liu, Y Feng, Y Lu, R Huang, Y Zhang, Y Zhao… - Science …, 2024 - science.org
Cancer vaccines show huge potential for cancer prevention and treatment. However, their
efficacy remains limited due to weak immunogenicity regarding inefficient stimulation of …