Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-
grade glioma. Rather than a “wait and see” policy, an aggressive attitude is now …

In recent years, advances in the understanding of low-grade glioma (LGG) biology have
driven new paradigms in molecular markers, diagnostic imaging, operative techniques and …

A detailed characterization study is presented of a Raman spectroscopy system designed to
maximize the volume of resected cancer tissue in glioma surgery based on in vivo molecular …

MRI has a vital role in the assessment of intracranial lesions. Conventional MRI has limited
specificity and multiparametric MRI using diffusion-weighted imaging, perfusion-weighted …

The optimal management of patients with low-grade glioma (LGG) is controversial. The
controversy largely stems from the lack of well-designed clinical trials with adequate follow …

The management of diffuse supratentorial WHO grade II glioma remains a challenge
because of the infiltrative nature of the tumor, which precludes curative therapy after total or …

Purpose: Recent artificial intelligence algorithms aided intraoperative decision-making via
stimulated Raman histology (SRH) during craniotomy. This study assesses deep learning …

Diffuse low-grade gliomas include oligodendrogliomas and astrocytomas. The recent 2016
WHO classification has now updated the definition of these tumors to include molecular …

Abstract Purpose of Review Isocitrate dehydrogenase (IDH) mutant gliomas are a distinct
type of primary brain tumors with unique characteristics, behavior, and disease outcomes …

BACKGROUND: The ability to diagnose brain tumors intraoperatively and identify tumor
margins during resection could maximize resection and minimize morbidity. Advances in …