The spinal cord integrates and relays somatosensory input, leading to complex motor
responses. Research over the past couple of decades has identified transcription factor …

The spinal cord of vertebrate animals is comprised of intrinsic circuits that are capable of
sensing the environment and generating complex motor behaviors. There are two major …

To elucidate the evolutionary origin of nervous system centralization, we investigated the
molecular architecture of the trunk nervous system in the annelid Platynereis dumerilii …

The develo** nervous system consists of a variety of cell types. Transgenic animals
expressing reporter genes in specific classes of neuronal cells are powerful tools for the …

Mutations in the human and mouse PTF1A/Ptf1a genes result in permanent diabetes
mellitus and cerebellar agenesis. We show that Ptf1a is present in precursors to GABAergic …

Sensory information from the periphery is integrated and transduced by excitatory and
inhibitory interneurons in the dorsal spinal cord. Recent studies have identified a number of …

During development, the three major neural cell lineages, neurons, oligodendrocytes and
astrocytes, differentiate in specific temporal orders at topologically defined positions. How …

The neural basic helix-loop-helix transcription factor Ascl1 (previously Mash1) is present in
ventricular zone cells in restricted domains throughout the develo** nervous system. This …

Neurons of the dorsal hindbrain and spinal cord are central in receiving, processing and
relaying sensory perception and participate in the coordination of sensory-motor output …

Although the role of developmental apoptosis in sha** the complement and connectivity of
sensory and motoneurons is well documented, the extent to which cell death affects the 13 …