Vagus nerve stimulation in brain diseases: Therapeutic applications and biological mechanisms

Y Wang, G Zhan, Z Cai, B Jiao, Y Zhao, S Li… - … & Biobehavioral Reviews, 2021 - Elsevier
Brain diseases, including neurodegenerative, cerebrovascular and neuropsychiatric
diseases, have posed a deleterious threat to human health and brought a great burden to …

Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial

J Dawson, CY Liu, GE Francisco, SC Cramer, SL Wolf… - The lancet, 2021 - thelancet.com
Background Long-term loss of arm function after ischaemic stroke is common and might be
improved by vagus nerve stimulation paired with rehabilitation. We aimed to determine …

[HTML][HTML] How to fail with paired VNS therapy

SA Hays, RL Rennaker II, MP Kilgard - Brain stimulation, 2023 - Elsevier
Vagus nerve stimulation (VNS) has gained enormous traction as a promising bioelectronic
therapy. In particular, the delivery of VNS paired with training to promote neural changes has …

Non-invasive brain stimulation techniques for the improvement of upper limb motor function and performance in activities of daily living after stroke: a systematic …

I Ahmed, R Mustafaoglu, S Rossi, FA Cavdar… - Archives of Physical …, 2023 - Elsevier
Objective To compare the efficacy of non-invasive brain stimulation (NiBS) such as
transcranial direct current stimulation (tDCS), repetitive transcranial magnetic stimulation …

[HTML][HTML] Left or right ear? A neuroimaging study using combined taVNS/fMRI to understand the interaction between ear stimulation target and lesion location in chronic …

X Peng, B Baker-Vogel, M Sarhan, EB Short, W Zhu… - Brain stimulation, 2023 - Elsevier
Background Implanted vagus nerve stimulation (VNS) and transcutaneous auricular VNS
(taVNS) have been primarily administered clinically to the unilateral-left vagus nerve. This …

Noninvasive brain stimulation for neurorehabilitation in post-stroke patients

KP Li, JJ Wu, ZL Zhou, DS Xu, MX Zheng, XY Hua… - Brain Sciences, 2023 - mdpi.com
Characterized by high morbidity, mortality, and disability, stroke usually causes symptoms of
cerebral hypoxia due to a sudden blockage or rupture of brain vessels, and it seriously …

Non-invasive Vagus nerve stimulation in cerebral stroke: current status and future perspectives

L Li, D Wang, H Pan, L Huang, X Sun, C He… - Frontiers in …, 2022 - frontiersin.org
Stroke poses a serious threat to human health and burdens both society and the healthcare
system. Standard rehabilitative therapies may not be effective in improving functions after …

Transcutaneous vagus nerve stimulation (tVNS) in stroke: the evidence, challenges and future directions

SS Baig, M Kamarova, A Ali, L Su, J Dawson… - Autonomic …, 2022 - Elsevier
Stroke is one of the leading causes of death and disability globally. A significant proportion
of stroke survivors are left with long term neurological deficits that have a detrimental effect …

Vagus nerve stimulation paired with rehabilitation for motor function, mental health and activities of daily living after stroke: a systematic review and meta-analysis

Y Gao, Y Zhu, X Lu, N Wang, S Zhu, J Gong… - Journal of Neurology …, 2023 - jnnp.bmj.com
Objective Vagus nerve stimulation (VNS) plus rehabilitation (Rehab) has shown a potential
effect on recovery with a stroke. We systematically synthesised studies examining VNS+ …

The adjunct of electric neurostimulation to rehabilitation approaches in upper limb stroke rehabilitation: a systematic review with network meta-analysis of randomized …

I Ahmed, I Yeldan, R Mustafaoglu - Neuromodulation: Technology at the …, 2022 - Elsevier
Objective This review analyzed the current evidence and the potential for the application of
electric neurostimulation such as transcranial direct current stimulation (tDCS) and vagus …