The clinical, molecular, and therapeutic features of patients with IL10/IL10R deficiency: a systematic review
N Sharifinejad, M Zaki-Dizaji… - Clinical and …, 2022 - academic.oup.com
Abstract Interleukin10 (IL10) and IL10 receptor (IL10R) deficiencies are monogenic inborn
errors of immunity (IEI) causing early-onset inflammatory bowel diseases (IBD). In this report …
errors of immunity (IEI) causing early-onset inflammatory bowel diseases (IBD). In this report …
A novel hypothesis for COVID-19 pathogenesis: Retinol depletion and retinoid signaling disorder
AR Sarohan, M Kızıl, AÇ İnkaya, S Mahmud, M Akram… - Cellular signalling, 2021 - Elsevier
The SARS-CoV-2 virus has caused a worldwide COVID-19 pandemic. In less than a year
and a half, more than 200 million people have been infected and more than four million …
and a half, more than 200 million people have been infected and more than four million …
Integrating 3D genomic and epigenomic data to enhance target gene discovery and drug repurposing in transcriptome-wide association studies
C Khunsriraksakul, D McGuire, R Sauteraud… - Nature …, 2022 - nature.com
Transcriptome-wide association studies (TWAS) are popular approaches to test for
association between imputed gene expression levels and traits of interest. Here, we propose …
association between imputed gene expression levels and traits of interest. Here, we propose …
Retinol Levels and Severity of Patients with COVID-19
MCC Carvalho, JKCP Araujo, AGCL da Silva… - Nutrients, 2023 - mdpi.com
The new coronavirus infection represents a serious threat to global health and economies.
In this sense, it is paramount to know the nutritional factors that may be related to the …
In this sense, it is paramount to know the nutritional factors that may be related to the …
Integrating AI/ML models for patient stratification leveraging omics dataset and clinical biomarkers from COVID-19 patients: A promising approach to personalized …
The COVID-19 pandemic has presented an unprecedented challenge to the healthcare
system. Identifying the genomics and clinical biomarkers for effective patient stratification …
system. Identifying the genomics and clinical biomarkers for effective patient stratification …
ANANASTRA: annotation and enrichment analysis of allele-specific transcription factor binding at SNPs
A Boytsov, S Abramov, AZ Aiusheeva… - Nucleic Acids …, 2022 - academic.oup.com
Abstract We present ANANASTRA, https://ananastra. autosome. org, a web server for the
identification and annotation of regulatory single-nucleotide polymorphisms (SNPs) with …
identification and annotation of regulatory single-nucleotide polymorphisms (SNPs) with …
Thrombocytopenia in COVID‑19 and vaccine‑induced thrombotic thrombocytopenia
SA Geronikolou, I Takan… - International …, 2022 - spandidos-publications.com
The highly heterogeneous symptomatology and unpredictable progress of COVID‑19
triggered unprecedented intensive biomedical research and a number of clinical research …
triggered unprecedented intensive biomedical research and a number of clinical research …
Spatial transcriptomic profiling of coronary endothelial cells in SARS-CoV-2 myocarditis
C Margaroli, P Benson, MG Gastanadui, C Song… - Frontiers in …, 2023 - frontiersin.org
Objectives Our objective was to examine coronary endothelial and myocardial programming
in patients with severe COVID-19 utilizing digital spatial transcriptomics. Background Severe …
in patients with severe COVID-19 utilizing digital spatial transcriptomics. Background Severe …
Inflammation and immunity connect hypertension with adverse COVID-19 outcomes
L Cai, C He, Y Liu, Y Sun, L He, A Baranova - Frontiers in Genetics, 2022 - frontiersin.org
Objectives: To explore the connection of hypertension and severe COVID-19 outcomes.
Methods: A total of 68 observational studies recording mortality and/or general severity of …
Methods: A total of 68 observational studies recording mortality and/or general severity of …
Integrative Transcriptomic Profiling of NK Cells and Monocytes: Advancing Diagnostic and Therapeutic Strategies for COVID-19.
S Loukman, R BENMRID, N Bouchmaa, H Hboub… - bioRxiv, 2024 - biorxiv.org
In this study, we use integrated transcriptomic datasets from the GEO repository with the
purpose of investigating immune dysregulation in COVID-19. Thus, in this context, we …
purpose of investigating immune dysregulation in COVID-19. Thus, in this context, we …